Structure of PDB 6zsc Chain AB Binding Site BS01

Receptor Information
>6zsc Chain AB (length=218) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DFNDKILNEPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEPYI
FGSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFISRNRQFSYLIE
NMARDCGEYAHTRYFRGGMLTNARLLFGPTVRLPDLIIFLHTLNNIFEPH
VAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRLFQTA
ITRAKEKRQQVEALYRLQ
Ligand information
>6zsc Chain AA (length=924) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucgaucaaaaggaaca
agcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagccacacc
cccacgggaaacagcagugauuaaccuuuagcaauaaacgaaaguuuaac
uaagcuauacuaaccccaggguuggucaauuucgugccagccaccgcggu
cacacgauuaacccaagucaauagaccggcguaaagaguguuuuagauca
caauaaagcuaaaacucaccugaguuguaaaaaacuccaguugacacaaa
auagacuacgaaaguggcuuuaacauaucugaacacacaauagcuaagac
ccaaacugggauuagauaccccacuaugcuuagcccuaaaccucaacagu
ucaacaaaacugcucgccagaacacuacgagccacagcuuaaaacucaaa
ggaccuggcggugcuucauaucccucuagaggagccuguucuguaaucga
uaaaccccgaucaaccucaccaccucuugcucagccuauauaccgccauc
uucagcaaacccugaugaaggcuacaaaguaagcgcaaguacccacguaa
agacguuaggucaagguguagcccaugagguggcaagaaaugggcuacau
uuucuaccccagaaacgauagcccuuaugaauaagggucgaagguggauu
uagcaguaaacuaagaguagagugcuuaguugaacagggcccugaagcgc
guacacaccgcccgucacccuccucaaguauacuucaaaggacuuaacua
aaaccccuacgcauuuauauagaggagacaagucguaacaugguaagugu
acuggaaagugcacuuggacgaac
..((((..<<<<<<.)))).<<<<<<.<...<<<<<<<<..<.<<<.<<<
..<......>......<<........<<<.<..<<..>>.>..>>>...<
<<<....<<...<<<....>>>..>>......>>>>.<<...>>.>>.<<
<....>>>.....>>>>>>>........<<<....<<<......>>>..>
>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>))...
....)))..>>>>>...>.>>>>>>..<<<((.....<<<<..<<<<...
...<<<<<<......<<<.<<<.<<<......>>>..>>>.>>>......
......<<<....>>>>>>>>>.....>>>>...>>>>....<<<<<<..
.<<...<<<<.<.....>.>>>>...>>>>>>>>..........<.<<<<
<..))..>>>>>.>.>>>.<<.......<<<<....>>>>.....>>..>
>>>>><<<<<.<<<<<<<...<<<.<<<<<..<<<<<<<<<<.....<<.
.......>>..........<<<<<<<.......<<.<<<..<<<<<<.<.
....<<..<<<<<.....>>>.......>>..>>.....<<<....>>>.
....>...>>>...>>>>>>>>....>>>>>>>..>>.>>>>>>>>....
.<<<<.....>>>>.<....<<<<<<<....>>>>>>>....>.....>>
>>>.....<<<<<<<.........>>>>>>>.....>>>...>>>>>>>>
>>.>>....<..<<.<...<<<<<<..<<<<<..<...<<<..<<.....
>>...>>>....>..>>>>>.>>>>>>....>.>>...>.....<<<<<<
<<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
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PDB6zsc Structural basis of mitochondrial translation.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
R147 R149 Y170 G173 G174 T177 N178 N200 N201 I202 V207 R210
Binding residue
(residue number reindexed from 1)
R91 R93 Y114 G117 G118 T121 N122 N144 N145 I146 V151 R154
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
GO:0061668 mitochondrial ribosome assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6zsc, PDBe:6zsc, PDBj:6zsc
PDBsum6zsc
PubMed32812867
UniProtQ9Y399|RT02_HUMAN Small ribosomal subunit protein uS2m (Gene Name=MRPS2)

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