Structure of PDB 6vlz Chain AB Binding Site BS01

Receptor Information
>6vlz Chain AB (length=220) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDFNDKILNEPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEPY
IFGSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFISRNRQFSYLI
ENMARDCGEYAHTRYFRGGMLTNARLLFGPTVRLPDLIIFLHTLNNIFEP
HVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRLFQT
AITRAKEKRQQVEALYRLQG
Ligand information
>6vlz Chain AA (length=944) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
gaacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucacccccaauaaagcuaaaacucaccugaguuguaaaaaacucca
guugacacaaaauagacuacgaaaguggcuuuaacauaucugaacacaca
auagcuaagacccaaacugggauuagauaccccacuaugcuuagcccuaa
accucaacaguuaaaucaacaaaacugcucgccagaacacuacgagccac
agcuuaaaacucaaaggaccuggcggugcuucauaucccucuagaggagc
cuguucuguaaucgauaaaccccgaucaaccucaccaccucuugcucagc
cuauauaccgccaucuucagcaaacccugaugaaggcuacaaaguaagcg
caaguacccacguaaagacguuaggucaagguguagcccaugagguggca
agaaaugggcuacauuuucuaccccagaaacgauagcccuuaugaaacuu
aagggucgaagguggauuuagcaguaaacuaagaguagagugcuuaguug
aacagggcccugaagcgcguacacaccgcccgucacccuccucaaguaua
cuucaaaggacauuuaacuaaaaccccuacgcauuuauauagaggagaca
agucguaacaugguaaguguacuggaaagugcacuuggacgaac
..((((..<<<<<<.)))).<<<<<<.....<<<<<<<<..<.<<<.<<<
..<......>......<<........<<<....<<<.....>>>....>>
>...<<<<....<<<..<<<....>>>.>>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>>........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>.....>>>>>>....<<<((.....<<<<..
<<<<..........<<<<<<......<<<.<<<.<<<......>>>..>>
>.>>>............<<<....>>>>>>>>>.....>>>>...>>>>.
..<<<<<<<...<<...<<<<.........>>>>...>>>>>>>>..>..
.....<.<<<<<......))..>>>>>.>.>>>.<<.......<<<<...
.>>>>.....>>..>>>>>><<<<<.<<<<<<<...<<<.<<<<...<<<
<<<<<<<.....<<........>>..........<<<<<<<.......<<
.<<<..<<<<<<.......<<..<<<<<.....>>>.......>>..>>.
....<<<....>>>.........>>>...>>>>>>>>....>>>>>>>..
>>.>>>>>>>>.....<<<<.....>>>>.......<<<<<.........
>>>>>............>>>>.....<<<<<<<.........>>>>>>>.
....>>>...>>>>>>>>>>.>>.......<<.<...<<<<<<..<<<<<
..<..........<.......>..........>..>>>>>.>>>>>>...
.>.>>.........<<<<<<<<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6vlz Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation.
Resolution2.97 Å
Binding residue
(original residue number in PDB)		R100 F101 E103 R147 R149 Y170 R172 G173 T177 N178 L182 N200 N201 I202 V207 R210 K214
Binding residue
(residue number reindexed from 1)		R45 F46 E48 R92 R94 Y115 R117 G118 T122 N123 L127 N145 N146 I147 V152 R155 K159
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
GO:0061668 mitochondrial ribosome assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6vlz, PDBe:6vlz, PDBj:6vlz
PDBsum6vlz
PubMed32737313
UniProtQ9Y399|RT02_HUMAN Small ribosomal subunit protein uS2m (Gene Name=MRPS2)

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