Structure of PDB 6r6g Chain AB Binding Site BS01

Receptor Information
>6r6g Chain AB (length=403) Species: 9615 (Canis lupus familiaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADLGRKITSALRSLSNATIINEEVLNAMLKEVCTALLEADVNIKLVKQLR
ENVKSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNV
IMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNAT
KARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFE
EMLQVANAIQPDNIVYVMDASIGQACEAQAKAFKDKVDVASVIVTKLDGH
AKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLGMQFTLRD
MYEQFQNIMKMGPFSQILGMIPGFGTDFMSKGNEQESMARLKKLMTIMDS
MNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRDVQELLTQYTKFAQMV
KKM
Ligand information
>6r6g Chain AF (length=206) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gccgggcgcgguggcgcgcgccuguagucccagcuacucgggaggcugag
gcuggaggaucgcuugacuaaguucggcaucaauauggugaccucccggg
agcgggggaccaccagguugccuaaggaggggugaaccggcccaggucgg
aaacggagcaggucaaaacucccgugcugaucaguaguuuagcgagaccc
cgucuc
<<<<<<<<<<..(((.>>>>>>>....<<<<.)))....>>>>>>>.<<<
<<.<<....<<<<<.<<<<.<..<<<<<<<<<<<.<<<<<..<<<<<<..
..>>>>>>..>>>>>.>>>>........<<<<<.....<<<<....<<<.
...>>>....>>>>...>>>>>.>>>>>>>....>>>>>.>>>>>...>>
.>>>>>
Receptor-Ligand Complex Structure
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PDB6r6g Structural and mutational analysis of the ribosome-arresting human XBP1u.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		T377 D380 S381 M382 N383 D384 Q399 G401 R402 R405 R408 G409 S410 G411
Binding residue
(residue number reindexed from 1)		T346 D349 S350 M351 N352 D353 Q368 G370 R371 R374 R377 G378 S379 G380
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6r6g, PDBe:6r6g, PDBj:6r6g
PDBsum6r6g
PubMed31246176
UniProtP61010|SRP54_CANLF Signal recognition particle subunit SRP54 (Gene Name=SRP54)

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