Structure of PDB 6nu3 Chain AB Binding Site BS01

Receptor Information
>6nu3 Chain AB (length=217) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FNDKILNEPLKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEPYIF
GSRLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFISRNRQFSYLIEN
MARDCGEYAHTRYFRGGMLTNARLLFGPTVRLPDLIIFLHTLNNIFEPHV
AVRDAAKMNIPTVGIVDTNCNPCLITYPVPGNDDSPLAVHLYCRLFQTAI
TRAKEKRQQVEALYRLQ
Ligand information
>6nu3 Chain AA (length=923) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucgaucaaaaggaaca
agcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagccacacc
cccacgggaaacagcagugauuaaccuuuagcaauaaacgaaaguuuaac
uaagcuauacuaaccccaggguuggucaauuucgugccagccaccgcggu
cacacgauuaacccaagucaauagaccggcguaaagaguguuuuagauca
caauaaagcuaaaacucaccugaguuguaaaaaacuccaguugacacaaa
auagacuacgaaaguggcuuuaacauaucugaacacacaauagcuaagac
ccaaacugggauuagauaccccacuaugcuuagcccuaaaccucaacagu
ucaacaaaacugcucgccagaacacuacgagccacagcuuaaaacucaaa
ggaccuggcggugcuucauaucccucuagaggagccuguucuguaaucga
uaaaccccgaucaaccucaccaccucuugcucagccuauauaccgccauc
uucagcaaacccugaugaaggcuacaaaguaagcgcaaguacccacguaa
agacguuaggucaagguguagcccaugagguggcaagaaaugggcuacau
uuucuaccccagaaacgauagcccuuaugaaauaagggucgaagguggau
uuagcaguaaacuaagaguagagugcuuaguugaacagggcccugaagcg
cguacacaccgcccgucacccuccucaaguauacuucaaaggacuuaacu
aaaaccccuacgcauuuauauagaggagacgucguaacaugguaagugua
cuggaaagugcacuuggacgaac
..((((..<<<<<<.)))).<<<<<<.<...<<<<<<<<..<.<<<.<<<
..<......>......<<........<<<....<<..>>....>>>...<
<<<....<<<..<<<....>>>.>>>......>>>>.<<...>>.>>.<<
<....>>>.....>>>>>>>........<<<....<<<<....>>>>..>
>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>))...
....)))..>>>>>...>.>>>>>>..<<<((......<<<..<<<<...
...<<<<<<........<...<.<<........>>..>...>........
.......<<....>>.>>>>>>.....>>>>...>>>....<<<<<<<..
.<<...<<<<.........>>>>...>>>>>>>>..>.......<.<<<<
<..))..>>>>>.>.>>>.<<.......<<<<....>>>>.....>>..>
>>>>><<<<<.<<<<<<<...<<<.<<<<<..<<<<<<<.<<.....<<.
.......>>..........<<<<<<<.......<<.<<<..<<<<<<...
....<<..<<<<<.....>>>.......>>..>>.....<<<....>>>.
........>>>...>>>>>>>>....>>>>>>>..>>..>>>>>>>....
...<<.....>>...<....<<<<<<.......>>>>>>....>.....>
>>>>.....<<<<<<<.........>>>>>>>.....>>>...>>>>>>>
>>>.>>........<.....<<<<<<...<<<<...........<.....
..>.............>>>>..>>>>>>....>..........<<<<<<<
<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6nu3 Structural insights into unique features of the human mitochondrial ribosome recycling.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		R100 R147 R149 Y170 F171 G173 G174 T177 N178 L181 N200 N201 I202 R210 K214
Binding residue
(residue number reindexed from 1)		R43 R90 R92 Y113 F114 G116 G117 T120 N121 L124 N143 N144 I145 R153 K157
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
GO:0061668 mitochondrial ribosome assembly
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6nu3, PDBe:6nu3, PDBj:6nu3
PDBsum6nu3
PubMed30962385
UniProtQ9Y399|RT02_HUMAN Small ribosomal subunit protein uS2m (Gene Name=MRPS2)

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