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Receptor Information

>4ujc Chain AB (length=611) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DSDDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPVICVLGHVDTG
KTKILDKLRHTHVQDQQIGATNVPLEAINEQTKMIKNFDRENVRIPGMLI
IDTPGHESFSNLRNRGSSLCDIAILVVDIMHGLEPQTIESINLLKSKKCP
FIVALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKAIIVEFAQ
QGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQTMLSKRL
AHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTIIVPGVEGPIVTQ
IRGLLLPPPQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPV
LKDELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGI
NIGPVHKKDVMKASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFS
AEIIYHLFDAFTKYRQDYKKQKQEEFKHIAVFPCKMKILPQYIFNSRDPI
VMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTSIEVNHKQVDVAKKGQEVC
VKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRDEMQKSDWQ
LIVELKKVFEI

>4ujc Chain AA (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gcccggauagcucagucgguagagcaggggauugaaaauccccguguccu
ugguucgauuccgaguccgggcacca

<<<<<<<..<<<<........>>>>.<<<<<<.....>>>>>>.....<<
<<<.......>>>>>>>>>>>>....

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4ujc Structure of the Mammalian 80S Initiation Complex with Initiation Factor 5B on Hcv-Ires RNA.
Resolution	9.5 Å
Binding residue (original residue number in PDB)	F1316 N1317 S1318 R1319 P1321 I1322 V1323 M1324 G1325 S1354 I1355 E1356 V1371 C1372 V1373 K1374 S1382 P1383 K1384 R1388
Binding residue (residue number reindexed from 1)	F494 N495 S496 R497 P499 I500 V501 M502 G503 S532 I533 E534 V549 C550 V551 K552 S560 P561 K562 R566

Enzyme Commision number

	Molecular Function
GO:0003924	GTPase activity
GO:0005525	GTP binding

PDB	RCSB:4ujc, PDBe:4ujc, PDBj:4ujc
PDBsum	4ujc
PubMed	25064512
UniProt	G1TRL5

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Structure of PDB 4ujc Chain AB Binding Site BS01