Structure of PDB 8qfy Chain AAA Binding Site BS01
Receptor Information
>8qfy Chain AAA (length=250) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWELVETRPAGDGTFQKWAAVTCHVQHEGLPEPVT
Ligand information
>8qfy Chain CCC (length=9) Species:
1773
(Mycobacterium tuberculosis) [
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RLPAKAPLL
Receptor-Ligand Complex Structure
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PDB
8qfy
An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis.
Resolution
2.33 Å
Binding residue
(original residue number in PDB)
Y7 H9 E63 I73 N77 T80 Y84 W97 H99 F116 E152 H155 Q156 Y159 Y171
Binding residue
(residue number reindexed from 1)
Y7 H9 E63 I73 N77 T80 Y84 W97 H99 F116 E152 H155 Q156 Y159 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:8qfy
,
PDBe:8qfy
,
PDBj:8qfy
PDBsum
8qfy
PubMed
38691588
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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