Structure of PDB 7qpw Chain AAA Binding Site BS01

Receptor Information
>7qpw Chain AAA (length=124) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRCKPVNTFVHES
LADVQAVCSQKNVACKNGQTNCYQSYSTMSITDCRETGSSKYPNCAYKTT
QANKHIIVACEGNPYVPVHFDASV
Ligand information
Ligand IDF5T
InChIInChI=1S/C2HF3O2.2C2H4O2.2H2O.2Rh/c3-2(4,5)1(6)7;2*1-2(3)4;;;;/h1H;2*2H,1H3;2*1H2;;/q3*-2;;;2*+5/p-2
InChIKeyAAVQFBAKNWVTEL-UHFFFAOYSA-L
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7CC1O[Rh+]23(OC(O[Rh+]2(O1)(OC(O3)C(F)(F)F)O)C)O
CACTVS 3.385C[CH]1O[Rh+]2(O)O[CH](C)O[Rh+](O)(O1)O[CH](O2)C(F)(F)F
CACTVS 3.385C[C@@H]1O[Rh+]2(O)O[C@@H](C)O[Rh+](O)(O1)O[C@H](O2)C(F)(F)F
FormulaC6 H11 F3 O8 Rh2
Namecis-bis(mi2-acetato-O, O')-(mi2-trifluoroacetato-O, O')-diaquo-dirhodium (II)
ChEMBL
DrugBank
ZINC
PDB chain7qpw Chain AAA Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB7qpw Reactivity of a fluorine-containing dirhodium tetracarboxylate compound with proteins.
Resolution1.15 Å
Binding residue
(original residue number in PDB)		Q11 V118 H119
Binding residue
(residue number reindexed from 1)		Q11 V118 H119
Annotation score1
Enzymatic activity
Enzyme Commision number 4.6.1.18: pancreatic ribonuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0004522 ribonuclease A activity
GO:0004540 RNA nuclease activity
GO:0005515 protein binding
GO:0016829 lyase activity
Biological Process
GO:0050830 defense response to Gram-positive bacterium
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7qpw, PDBe:7qpw, PDBj:7qpw
PDBsum7qpw
PubMed35166290
UniProtP61823|RNAS1_BOVIN Ribonuclease pancreatic (Gene Name=RNASE1)

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