Structure of PDB 7oit Chain AAA Binding Site BS01

Receptor Information
>7oit Chain AAA (length=258) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSGM
PECKFGMNDKIVIEQSIAIDDCTFHQCVRLSKFDSERSISFIPPDGEFEL
MRYRTTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRI
PTPLNTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLP
TNDWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGR
SGIYETRC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oit FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		F174 K405 D415 K420 W421 V422 R423
Binding residue
(residue number reindexed from 1)		F15 K228 D238 K243 W244 V245 R246
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7oit, PDBe:7oit, PDBj:7oit
PDBsum7oit
PubMed35486718
UniProtA0A140TAH5

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