Structure of PDB 7oiq Chain AAA Binding Site BS01

Receptor Information
>7oiq Chain AAA (length=257) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IGWRREGIKYRRNELFLDVLESVNLLMSPQGQVLSAHVSGRVVMKSYLSG
MPECKFGMNDKIVAIDDCTFHQCVRLSKFDSERSISFIPPDGEFELMRYR
TTKDIILPFRVIPLVREVGRTKLEVKVVIKSNFKPSLLAQKIEVRIPTPL
NTSGVQVICMKGKAKYKASENAIVWKIKRMAGMKESQISAEIELLPTNDK
KKWARPPISMNFEVPFAPSGLKVRYLKVFEPKLNYSDHDVIKWVRYIGRS
GIYETRC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7oiq FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P 2 -dependent switch.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		F174 D415 K420 W421 V422 R423
Binding residue
(residue number reindexed from 1)		F16 D237 K242 W243 V244 R245
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
Cellular Component
GO:0030131 clathrin adaptor complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7oiq, PDBe:7oiq, PDBj:7oiq
PDBsum7oiq
PubMed35486718
UniProtP84092|AP2M1_RAT AP-2 complex subunit mu (Gene Name=Ap2m1)

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