Structure of PDB 7ndu Chain AAA Binding Site BS01
Receptor Information
>7ndu Chain AAA (length=276) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQCAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP
Ligand information
>7ndu Chain CCC (length=9) Species:
11676
(Human immunodeficiency virus 1) [
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RMYSPVSIK
Receptor-Ligand Complex Structure
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PDB
7ndu
Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
Y7 H9 R62 E63 S66 T70 I73 N77 T80 Y84 W97 H99 E114 C116 S143 K146 H155 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 H9 R62 E63 S66 T70 I73 N77 T80 Y84 W97 H99 E114 C116 S143 K146 H155 Q156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7ndu
,
PDBe:7ndu
,
PDBj:7ndu
PDBsum
7ndu
PubMed
35108401
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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