Structure of PDB 7ndt Chain AAA Binding Site BS01
Receptor Information
>7ndt Chain AAA (length=271) Species:
9606
(Homo sapiens) [
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SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDGRFLRGYEQCAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGQDTELVETRPAGDGTFQKWAAVVVPSGEEQ
RYTCHVQHEGLPEPVTLRWKP
Ligand information
>7ndt Chain CCC (length=9) Species:
9606
(Homo sapiens) [
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VMAPRTLIK
Receptor-Ligand Complex Structure
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PDB
7ndt
Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Resolution
2.999 Å
Binding residue
(original residue number in PDB)
Y7 H9 E63 S66 A67 I73 F74 N77 T80 Y84 L95 W97 H99 C116 W133 S143 E152 H155 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 H8 E62 S65 A66 I72 F73 N76 T79 Y83 L94 W96 H98 C115 W132 S142 E151 H154 Q155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7ndt
,
PDBe:7ndt
,
PDBj:7ndt
PDBsum
7ndt
PubMed
35108401
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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