Structure of PDB 7ndq Chain AAA Binding Site BS01

Receptor Information
>7ndq Chain AAA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP
Ligand information
>7ndq Chain CCC (length=9) Species: 11676 (Human immunodeficiency virus 1) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RMYSPVSIL
Receptor-Ligand Complex Structure
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PDB7ndq Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Resolution2.551 Å
Binding residue
(original residue number in PDB)
Y7 E63 S66 T70 I73 N77 T80 Y84 W97 E114 S143 K146 H155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 S66 T70 I73 N77 T80 Y84 W97 E114 S143 K146 H155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7ndq, PDBe:7ndq, PDBj:7ndq
PDBsum7ndq
PubMed35108401
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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