Structure of PDB 7ndq Chain AAA Binding Site BS01
Receptor Information
>7ndq Chain AAA (length=276) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP
Ligand information
>7ndq Chain CCC (length=9) Species:
11676
(Human immunodeficiency virus 1) [
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RMYSPVSIL
Receptor-Ligand Complex Structure
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PDB
7ndq
Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.
Resolution
2.551 Å
Binding residue
(original residue number in PDB)
Y7 E63 S66 T70 I73 N77 T80 Y84 W97 E114 S143 K146 H155 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 S66 T70 I73 N77 T80 Y84 W97 E114 S143 K146 H155 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7ndq
,
PDBe:7ndq
,
PDBj:7ndq
PDBsum
7ndq
PubMed
35108401
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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