Structure of PDB 6toq Chain AAA Binding Site BS01

Receptor Information
>6toq Chain AAA (length=329) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLLHIRDVPPADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSE
MVEYITHNRNVITEPIYPEVVHMFAVNMFRTLPPDEPTLEAAWPHLQLVY
EFFLFLESPDFQPNIAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRI
YGKFLGLRAYIRKQINNIFYRFIYETEHHNGIAELLEILGSIINGFALPL
KEEHKIFLLKVLLPLHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMAL
LKYWPPKEVMFLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVA
ERALYYWNNEYIMSLISDNAAKILPIMFP
Ligand information
>6toq Chain CCC (length=7) Species: 11908 (Human T-cell leukemia virus type I) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RLQPIPE
Receptor-Ligand Complex Structure
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PDB6toq Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56 gamma.
Resolution3.164 Å
Binding residue
(original residue number in PDB)		H187 Y190 R197 S230 I231 G234
Binding residue
(residue number reindexed from 1)		H148 Y151 R158 S191 I192 G195
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019888 protein phosphatase regulator activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0000159 protein phosphatase type 2A complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6toq, PDBe:6toq, PDBj:6toq
PDBsum6toq
PubMed33028863
UniProtQ13362|2A5G_HUMAN Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (Gene Name=PPP2R5C)

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