Structure of PDB 4v6x Chain AA Binding Site BS01

Receptor Information
>4v6x Chain AA (length=208) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGALDVLQMKEEDVLKFLAAGTHLGGTNLDFQMEQYIYKRKSDGIYIINL
KRTWEKLLLAARAIVAIENPADVSVISSRNTGQRAVLKFAAATGATPIAG
RFTPGTFTNQIQAAFREPRLLVVTDPRADHQPLTEASYVNLPTIALCNTD
SPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLRMRGTISREHPWEVMPDL
YFYRDPEE
Ligand information
>4v6x Chain B2 (length=1861) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucucccacuuggauaa
cugugguaauucuagagcuaauacaugccgacgggcgcugacccccuucg
cgggggggaugcgugcauuuaucagaucaaaaccaacccggucagccccu
cuccggccccggccggggggcgggcgccggcggcuuuggugacucuagau
aaccucgggccgaucgcacgccccccguggcggcgacgacccauucgaac
gucugcccuaucaacuuucgaugguagucgccgugccuaccauggugacc
acgggugacggggaaucaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacucccga
cccggggagguagugacgaaaaauaacaauacaggacucuuucgaggccc
uguaauuggaaugaguccacuuuaaauccuuuaacgaggauccauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguugcugcaguuaaaaagcucguaguuggaucuugggagcgggcg
ggcgguccgcgagccaccgcccguccccgccccuugccucucggcgcccc
cucgaugcucuuagcugagugucccgcggggcccgaagcguuuacuuuga
aaaaauuagaguguucaaagcaggcccgagccgccuggauaccgcagcua
ggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaacuga
ggccaugauuaagagggacggccgggggcauucguauugcgccgcuagag
gugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuugcca
agaauguuuucauuaaucaagaacgaaagucggagguucgaagacgauca
gauaccgucguaguuccgaccauaaacgaugccgaccggcgaugcggcgg
cguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuuugg
guuccggggggaguaugguugcaaagcugaaacuuaaaggaauugacgga
agggcaccaccaggaguggagccugcggcuuaauuugacucaacacggga
aaccucacccggcccggacacggacaggauugacagauugauagcucuuu
cucgauuccgugggugguggugcauggccguucuuaguugguggagcgau
uugucugguuaauuccgauaacgaacgagacucuggcaugcuaacuaguu
acgcgacccccgagcggucggcgucccccaacuucuuagagggacaagug
gcguucagccacccgagauugagcaauaacaggucugugaugcccuuaga
uguccggggcugcacgcgcgcuacacugacuggcucagcgugugccuacc
cuacgccggcaggcgcggguaacccguugaaccccauucgugauggggau
cggggauugcaauuauuccccaugaacgaggaauucccaguaagugcggg
ucauaagcuugcguugauuaagucccugcccuuuguacacaccgcccguc
gcuacuaccgauuggaugguuuagugaggcccucggaucggccccgccgg
ggucggcccacggcccuggcggagcgcugagaagacggucgaacuugacu
aucuagaggaaguaaaagucguaacaagguuuccguaggugaaccugcgg
aaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[....................<<.....
<<.<<<.....>>>.>>......>>.........<<<<...<<<<<<...
.>>>>>>...>>>>[[..(((((.....<<<<<<<<<<<<.<..<<<<<<
<<<<<<<....>>>>>>>>>.>>>>....>>>>..............)))
))......]]...<<<<.<<<<......>>>>>>>>....]]]...}}..
..]]].<<<....<<<....<<<<<<<.........>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.........
.>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<..
...>>>..>>>......}}.......<<<<<<<<<.<<<....>>>.>.>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..)))))).
]]]............{{.......{{...[[[.[[....<<<.<.<<<<<
<<<<<<.<<>>....>>>>>>>>>>>.>.>>>...<<...<<<..<<<<<
...<<<<<<<......>>>>>>>....>>>>>.>>>.>>..<<<<<..<.
......<<...<.......>.<<<<.......>>>>...>>......>..
>>..>>>.......[[....(((((((.....>>>>>>>>>.))))))).
..]]....]]....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<
......>>>......>>>>>>>.>.>>.......<<....>>...>>>>.
.>..>>>.>>>...]]]...}}......<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<
.<<<<......>>>>>>>>>>.>..>>>...<<..}}>>...>>.....>
>>.....<<<......<<<......>>>....>>>..]]]]..<<<<<.<
<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>...
.......<<<<<......<<<<<<.......<<.<<<........>>>.>
>.....>>>>>>.<.<<.<<<..<<<<<<<<<....<<<.<<<<<....>
>>...<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<
....<<<..<<<<....>>>>.>>>....>>>>..>>>>..>.....<<<
<<.....>>>>>........>>>....>>>.>>>...>.>>>>>>>>...
...>>>>>...>>.>>>>.>>>.....<<.<<<........<.......<
<<.<<<<....>>>>.>>>....>.........>>>.>>...........
.<<<<<..........>>>>>...........>>>>>.....<<<<<<<<
.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<
..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<
<<<<<.....>>>>>>>>>>>>...>>>>>...>>.>>>>..>>>.>>>>
>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<....>>>>>>>
>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v6x Structures of the human and Drosophila 80S ribosome.
Resolution5.0 Å
Binding residue
(original residue number in PDB)		F32 R102 P105 N110 Q132 Y139 R155
Binding residue
(residue number reindexed from 1)		F31 R101 P104 N109 Q131 Y138 R154
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0001618 virus receptor activity
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005055 laminin receptor activity
GO:0005515 protein binding
GO:0043022 ribosome binding
GO:0043236 laminin binding
Biological Process
GO:0000028 ribosomal small subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0007155 cell adhesion
GO:0046718 symbiont entry into host cell
GO:0140374 antiviral innate immune response
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:0015935 small ribosomal subunit
GO:0016020 membrane
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0070062 extracellular exosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v6x, PDBe:4v6x, PDBj:4v6x
PDBsum4v6x
PubMed23636399
UniProtP08865|RSSA_HUMAN Small ribosomal subunit protein uS2 (Gene Name=RPSA)

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