Structure of PDB 6lqp Chain A5 Binding Site BS01

Receptor Information
>6lqp Chain A5 (length=514) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DSPVLQSAYDPSGQYLCYVTVALDKQRVGVQPTQRATWNENFLYLEDSKL
KVTCLKWVNDTVAIILGMNNGEIWLYSVLANEVTYKFTTGNSYEIKDIDL
MGNQLWCIDSSDAFYQFDLLQFKLLQHFRINNCVQLNKLTIVPAGDSVAQ
LLVASHSISLIDIEEKKVVMTFPGHVSPVSTLQVITNEFFISGAEGDRFL
NVYDIHSGMTKCVLVAESDIKELSHSGQADSIAVTTEDGSLEIFVDPLVS
GNKSKKSSKKIQIVSKDGRKVPIYNAFINKDLLNVSWLQNATMPYFKNLQ
WREIPNEYTVEISLNWNNKNKSADRDLHGKDLASATNYVEGNARVTSGDN
FKHVTATTTGTVTVILSQALQSNDHSLLETVLNNRDERVIRDTIFRLKPA
LAVILLERLAERIARQTHRQGPLNVWVKWCLIIHGGYLVSIPNLMSTLSS
LHSTLKRRSDLLPRLLALDARLDCTINKFKTLNYEAGDIHSSEPVVEEDE
DDVEYNEELDDAGL
Ligand information
>6lqp Chain 5A (length=523) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcgaaagcaguugaagacaaguggcuugucguucguuaaaauggccucg
ucaaacgguggagagagucgcuaggugaucgucagaucugccuagucucu
auacagcguguuuaauugacauggguugaugcguauugagagauacaauu
ugggaagaaauucccagaguguguuucuuuugcguuuaaccugaacaguc
ucaucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggug
gauuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaau
gccuuguugaauagccggucgcaagacugugauucuucaaguguaaccuc
cucucaaaucagcgauaucaaacguaccaccgugaaacaccgggguaucu
guuugguggaaccugauuagaggaaacucaaagagugcuaugguauggug
acggagugcgcuggucaagaguguaaaagcuuuuugaacagagagcauuu
ccggcagcagagauuucagcugu
<<<....>>>...<<<<<<<<<<.>>>>>>>.>>>..............<
<<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>
...>>.>>>......>>>>>..<<<<<..........<<<<<<<<<<.<<
<<<<<<....>>>>>>>.>>>>>>>>>>>........>>>>>.......<
<<<<<<<<<<...........>>>>>.>>>>>>.................
........<<<...>>>.........................<<<<<..<
<<<<<<..<<<<...<<<<<....>>>>>.>.>>>..>>>>.>>.>>>>>
>.....<<<<<<...<<<<<<<<<<<<<.<<<........>>>>>>>.>.
>>>>>>>>....>>>>>>................................
.<<<<.<<<.<<<.<<<<<<<<......>>>>.>>>>.>>>...>>>..>
>>><<<<<.<<<..>>>.>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6lqp Cryo-EM structure of 90 S small ribosomal subunit precursors in transition states.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		N360 R362 R460 R490 Q491 H493 R494
Binding residue
(residue number reindexed from 1)		N342 R344 R385 R415 Q416 H418 R419
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0045943 positive regulation of transcription by RNA polymerase I
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0032040 small-subunit processome
GO:0033553 rDNA heterochromatin
GO:0034455 t-UTP complex
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6lqp, PDBe:6lqp, PDBj:6lqp
PDBsum6lqp
PubMed32943522
UniProtQ04177|UTP5_YEAST U3 small nucleolar RNA-associated protein 5 (Gene Name=UTP5)

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