Structure of PDB 7tbm Chain A4 Binding Site BS01

Receptor Information

>7tbm Chain A4 (length=1269) Species: 9606 (Homo sapiens)

DLPPVAKAAQVVNQTLQLDDSYPDLDSYCRPGASSDYEMQSSDSSWAPFH
VVRHHNIPDKVFEHLNAGEVFTKLGLFAEIGYAWASIDSSLFLWDYTHPN
PELIGYEEATHTITAVALVPPKPGVFVKTITHVLVVATTSEIILLGVSAT
PTPSGSKSLTLYSTRMSVHRGGSDVSFIVGTKDGRIFLGGESDTDIHEIF
YQQEERWFSSRCGKINHSHPFGSRQQEWLRGLYVDDTRNLLYSLSNRSTI
RTYHMEGPEKLTKVIEKDKTSCLRDFAHMADSSPLFTDKTNIVALSPIPA
TEASKLHLMALTDTGCRLFLSATSSALAPQSMQLQFVKFPPRESPTRIRT
LNSQLDKTSRALDPSALGFRFSPGYFFDVVRKHPNQDMLFVSAPDTGRIK
VTQPASALKYFEQGTWIELENGNRTIEIGLTTAPFAAAKQPLGFGNELAV
QFDQVPGEFAVLTNTGVHIVRRRRLVDIFAKALGNCVSASDDALEREVRK
FINQYGRVETIAAALAVACGQGSMDRNTENLARAAFIEYGGQPRLAAESV
RLSSRHDALALYLTRLVRTLWKAKVVQVGSGSDISSTIPTLVTIQENVER
LRNFLEANKSTIQGLAPPEDIANQKEHQALHALQKLMESISEGISFVLML
FDERVSDIYARLDAVSQQQLKDLTYEQLFSQTPGKELAKVLVKAIVNRNI
AAPDDVVTFKAQEQLQRASEQAHNAPVLRALLAESLRLFEQVAGSLTPAN
LTTAVEQMISLKYYAGAIQLCLTVAQQKDRGNTALSWVNDGKPANDSRKK
AFDERKICYNLIHQVLDKLESDFAGEPELVDGRPTLAATKRMEAYNVVND
SSDEVFHFDMYEWYIEKGWTDRILSIDSPHVITYLQRLAETDFRHAELLC
RFYTTRSRFFEAAQVQTNLAKSDLNISLKDRIILLSRAKGNASVNTIGIS
RQQQQQLNHEASELLEIAHIQDDLLERLVADPRIPEERKAEIEEFLDGPI
RTLTDLFNDYADQANYYDLCLLIFHAADFHNPRTIMDTWNNLINQSHFEA
EQRREYWEIVQAGGDLPAGVIAPIAEPPLPYVYVSQQIQLIAHRTSLDSL
IFPVNSLLPVVCAYAINNGQDASIGADPCWPIQLFLNLGVPHALMVQVLE
NVLDTQEAPFTGRRRKLVVQWIAMAVDMWVREVERRGAMAAAAASGASGS
EAVMGSWVSELLGRADQVLTQIAGTGATLRGGAASDAEEIASLRRTVKGL
KRSVDMLLGGEMARMSFFR

Ligand information

>7tbm Chain B4 (length=14) Species: 9606 (Homo sapiens)

RKAKLLPMEEALLP

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7tbm Architecture of the cytoplasmic face of the nuclear pore.
• Resolution: 37.0 Å
• Binding residue (original residue number in PDB): G178 V198 F199 V200 I203 L234 Y235 R238 Q276
• Binding residue (residue number reindexed from 1): G105 V125 F126 V127 I130 L161 Y162 R165 Q203

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Nov 23 04:43:35 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '7tbm', asym_id = 'A4', bs = 'BS01', title = 'Architecture of the cytoplasmic face of the nuclear pore.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='7tbm', asym_id='A4', bs='BS01', title='Architecture of the cytoplasmic face of the nuclear pore.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0005643,0006913,0017056', uniprot = '', pdbid = '7tbm', asym_id = 'A4'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0005643,0006913,0017056', uniprot='', pdbid='7tbm', asym_id='A4')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>