Structure of PDB 7qi6 Chain A4 Binding Site BS01

Receptor Information
>7qi6 Chain A4 (length=588) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEVVIPKKKTWDKVAVLQALASTVNRDTTAVPYVFQDDPYLMPASSLESR
SFLLAKKSGENVAKFIINSYPKYFQKDIAEPHIPCLMPEYFEPQIKDISE
AALKERIELRKVKASVDMFDQLLQAGTTVSLETTNSLLDLLCYYGDQEPS
TDYHQFGVTWRAKNNAERIFSLMPEKNEHSYCTMIRGMVKHRAYEQALNL
YTELLNNRLHADVYTFNALIEATVCAINEKFEEKWSKILELLRHMVAQKV
KPNLQTFNTILKCLRRFHVFARSPALQVLREMKAIGIEPSLATYHHIIRL
FDQPGDPLKRSSFIIYDIMNELMGKRFSPKDPDDDKFFQSAMSICSSLRD
LELAYQVHGLLKTGDNWKFIGPDQHRNFYYSKFFDLICLMEQIDVTLKWY
EDLIPSAYFPHSQTMIHLLQALDVANRLEVIPKIWKDSKEYGHTFRSDLR
EEILMLMARDKHPPELQVAFADCAADIKSAYESQPIRQTAQDWPATSLNC
IAILFLRAGRTQEAWKMLGLFRKHNKIPRSELLNELMDSAKVSNSPSQAI
EVVELASAFSLPICEGLTQRVMSDFAINQEQKEALSNL
Ligand information
>7qi6 Chain Az (length=33) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaaaugguaguuuauaaaaaaauuuacuuaaa
.................................
Receptor-Ligand Complex Structure
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PDB7qi6 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
Resolution2.98 Å
Binding residue
(original residue number in PDB)
L101 R343 R344 R377 K414 Q417 H453 N455 F456 S459 D463 H489 S490 Q491 R524
Binding residue
(residue number reindexed from 1)
L47 R265 R266 R299 K336 Q339 H375 N377 F378 S381 D385 H411 S412 Q413 R446
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0006417 regulation of translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005763 mitochondrial small ribosomal subunit
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7qi6, PDBe:7qi6, PDBj:7qi6
PDBsum7qi6
PubMed38769321
UniProtQ96EY7|PTCD3_HUMAN Small ribosomal subunit protein mS39 (Gene Name=PTCD3)

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