Structure of PDB 7d5s Chain A4 Binding Site BS01

Receptor Information
>7d5s Chain A4 (length=662) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ERMIVHRCRFVDFTPATITSLAFSHKSNINKLTPSDLRLAIGRSNGNIEI
WNPRNNWFQEMVIEGGKDRSIEGLCWSNVNGESLRLFSIGGSTVVTEWDL
ATGLPLRNYDCNSGVIWSISINDSQDKLSVGCDNGTVVLIDISGGPGVLE
HDTILMRQEARVLTLAWKKDDFVIGGCSDGRIRIWSAQKNDENMGRLLHT
MKVDKAKKESTLVWSVIYLPRTDQIASGDSTGSIKFWDFQFATLNQSFKA
HDADVLCLTTDTDNNYVFSAGVDRKIFQFSQNTNKSQKNNRWVNSSNRLL
HGNDIRAICAYQSKGADFLVSGGVEKTLVINSLTSFSNGNYRKMPTVEPY
SKNVLVNKEQRLVVSWSESTVKIWTMGNYKLVCKLTLKDDQNISTCSLSP
DGQVLVVGRPSTTKVFHLQPVGNKLKVTKLDNDLLLRTSTKLVKFIDNSK
IVICSCEDDVFIVDQEVELLEVTSTKSSIKVPYINRINHLEVDQNIAVIS
RGCGVVDILDLKARISKPLARLNNFITAVHINTSRKSVVVITADNKIYEF
NMNVLTQWSKNNTDNLPKEWKTLKENCVGIFSDIENSSRLWFWGATWISR
IDFDVDFPINLTITDESNFMNDHFFFTDKYKPLLFVDLISSNELAIIERN
PQKAFIQPKLVF
Ligand information
>7d5s Chain 5A (length=523) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugcgaaagcaguugaagacaaguggcuugucguucguuaaaauggccucg
ucaaacgguggagagagucgcuaggugaucgucagaucugccuagucucu
auacagcguguuuaauugacauggguugaugcguauugagagauacaauu
ugggaagaaauucccagaguguguuucuuuugcguuuaaccugaacaguc
ucaucgugggcaucuugcgauuccauuggugagcagcgaaggauuuggug
gauuacuagcuaauagcaaucuauuucaaagaauucaaacuugggggaau
gccuuguugaauagccggucgcaagacugugauucuucaaguguaaccuc
cucucaaaucagcgauaucaaacguaccaccgugaaacaccgggguaucu
guuugguggaaccugauuagaggaaacucaaagagugcuaugguauggug
acggagugcgcuggucaagaguguaaaagcuuuuugaacagagagcauuu
ccggcagcagagauuucagcugu
<<<....>>>...<<<<<<<<<<.>>>>>>>.>>>..............<
<<<<<<<.<<...<<<<..<<<<<<<<<<<....>>>>.>>>>>>>>>>>
...>>.>>>......>>>>>..<<<<<..........<<<<<<<<<<.<<
<<<<<<....>>>>>>>.>>>>>>>>>>>........>>>>>.......<
<<<<<<<<<<...........>>>>>.>>>>>>.................
........<<<...>>>.........................<<<<<..<
<<<<<<..<<<<...<<<<<....>>>>>.>.>>>..>>>>.>>.>>>>>
>.....<<<<<<...<<<<<<<<<<<<<.<<<........>>>>>>>.>.
>>>>>>>>....>>>>>>................................
.<<<<.<<<.<<<.<<<<<<<<......>>>>.>>>>.>>>...>>>..>
>>><<<<<.<<<..>>>.>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7d5s Cryo-EM structure of 90S preribosome with inactive Utp24 (state A2)
Resolution4.6 Å
Binding residue
(original residue number in PDB)		K236 E237 S238 K303 L327 Q771 P772 K773 L774
Binding residue
(residue number reindexed from 1)		K208 E209 S210 K275 L299 Q657 P658 K659 L660
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0006364 rRNA processing
GO:0030490 maturation of SSU-rRNA
GO:0042254 ribosome biogenesis
GO:0045943 positive regulation of transcription by RNA polymerase I
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030686 90S preribosome
GO:0032040 small-subunit processome
GO:0034455 t-UTP complex
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7d5s, PDBe:7d5s, PDBj:7d5s
PDBsum7d5s
PubMed
UniProtQ06679|UTP4_YEAST U3 small nucleolar RNA-associated protein 4 (Gene Name=UTP4)

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