Structure of PDB 7qi6 Chain A2 Binding Site BS01

Receptor Information
>7qi6 Chain A2 (length=117) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATPSLRGRLARFGNPRKPVLKPNKPLILANRVGERRREKGEATCITEMSV
MMACWKQNEFRDDACRKEIQGFLDCAARAQEARKMRSIQETLGESGSLLP
NKLNKLLQRFPNKPYLS
Ligand information
>7qi6 Chain AA (length=954) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucaccacgaucaaaag
ggacaagcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagcc
acacccccacgggaaacagcagugauuaaccuuuagcaauaaacgaaagu
uuaacuaagcuauacuaaccccaggguuggucaauuucgugccagccacc
gcggucacacgauuaacccaagucaauagaagccggcguaaagaguguuu
uagaucacccccuccccaauaaagcuaaaacucaccugaguuguaaaaaa
cuccaguugacacaaaauagacuacgaaaguggcuuuaacauaucugaac
acacaauagcuaagacccaaacugggauuagauaccccacuaugcuuagc
ccuaaaccucaacaguuaaaucaacaaaacugcucgccagaacacuacga
gccacagcuuaaaacucaaaggaccuggcggugcuucauaucccucuaga
ggagccuguucuguaaucgauaaaccccgaucaaccucaccaccucuugc
ucagccuauauaccgccaucuucagcaaacccugaugaaggcuacaaagu
aagcgcaaguacccacguaaagacguuaggucaagguguagcccaugagg
uggcaagaaaugggcuacauuuucuaccccagaaaacuacgauagcccuu
augaaacuuaagggucgaagguggauuuagcaguaaacugagaguagagu
gcuuaguugaacagggcccugaagcgcguacacaccgcccgucacccucc
ucaaguauacuucaaaggacauuuaacuaaaaccccuacgcauuuauaua
gaggagacaagucguaacaugguaaguguacuggaaagugcacuuggacg
aacc
..((((..<<<<<<.)))).<<<<<<.<<..<<<<<<<<....<<<.<<<
..<......>......<<.......<<<<.<..<<<.....>>>.>..>>
>>..<<<<....<<...<<<....>>>..>>......>>>>.<<...>>.
>>.<<<....>>>.....>>>>>>.........<<<....<<<<....>>
>>..>>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>
)).......)))..>>>>>..>>.>>>>>>....<<<((.....<<<<..
<<<<...............<<<<<<......<<<.<<<.<<<......>>
>..>>>.>>>.............<<....>>.>>>>>>.....>>>>...
>>>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>
..........<.<<<<<......))..>>>>>.>.>>>.<<.......<<
<<....>>>>.....>>..>>>>>><<<<<.<<<<<<<...<<<.<<<<<
..<<<<<<<<<<.....<<........>>..........<<<<<<<....
...<<.<<<..<<<<<<.......<<..<<<<<.....>>>.......>>
..>>.....<<<....>>>.........>>>...>>>>>>>>....>>>>
>>>..>>.>>>>>>>>.....<<<<.....>>>>.....<....<<<<<<
<.......>>>>>>>....>.....>>>>>.....<<<<<<<........
.>>>>>>>.....>>>...>>>>>>>>>>.>>....<..<<.<...<<<<
<<..<<<<<......<<<....<<.....>>...>>>.......>>>>>.
>>>>>>....>.>>...>.....<<<<<<<<<....>>>>>>>>>.....
....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7qi6 Structure of mitoribosome reveals mechanism of mRNA binding, tRNA interactions with L1 stalk, roles of cofactors and rRNA modifications.
Resolution2.98 Å
Binding residue
(original residue number in PDB)		R9 A11 R12 F13 R17 K18 P19 V20 K22 N24 K25 R32 G34 E35 R36 R37 R38 K85 S98 L99 K106 Q109 R110
Binding residue
(residue number reindexed from 1)		R8 A10 R11 F12 R16 K17 P18 V19 K21 N23 K24 R31 G33 E34 R35 R36 R37 K84 S97 L98 K105 Q108 R109
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0001650 fibrillar center
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005763 mitochondrial small ribosomal subunit
GO:0005829 cytosol
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7qi6, PDBe:7qi6, PDBj:7qi6
PDBsum7qi6
PubMed38769321
UniProtQ96BP2|CHCH1_HUMAN Small ribosomal subunit protein mS37 (Gene Name=CHCHD1)

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