Structure of PDB 7pwo Chain A2 Binding Site BS01 |
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| >7pwo Chain 1 (length=2448)
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cggcccgaggcggcgggggcgacgggcggaacuuaagcauaucaguacgc
cccggaggagaaaccaaccgggauuccccguagcggcgagcgacgcggga
ggagcccgccccgaaggcgcgcugugggcgccgcgagggggcccgagggc
cccgcccgagagggugcaagccccguacggcgggcgaguagcgcugcuug
agcgugcagcgcgaagggaggcgcggcccuuccaaggcuaaauacgcccc
gggaccgauagcggaccaaguagcgcgagcgaacggugaaaaggacgccc
ggccgcucaaaagaccugaacccggccggcgccggcccgccggccccguc
ucgaaacacggaccgaggagccacgcgccgcggcgagcccgagggccccg
cggcggagcgagcgcgagacgccccgggcccgccgcgccccugcgggcgu
gcgcgggccgagccgcggcgcgugggcccgaaaggcggugaucuaugccc
ggcgagggcgaggccgggcgaaagccugguggaggcccgccgcggugcug
acgcgcagaucgcucgucggagccgggcaugggggcgaaagacucaucga
accgccugguagcugguugccuccgaaaugucucccaggacagccgccgc
ccgcaguugcggcccguagagcgcuggccggcggccgccccccaaacucc
gaagggccgcgccgccccgcccuggccugggcggggcgggcgaaugcggg
cggcgcgugggccccuccugguaagcaggacgggcgaggcgggacgaucc
ggacgccgggccagggugcgccgccggggccggaacggcgucggccgcgg
ccggcccggaaaauggagcgcgccggagccccggacccgcgcccggccgc
cgcgcgcggcggguaggaggccgcagaggccccgggggcgaaggcggcgc
gcaggccccgccggaccggccucuggugcagaucucggcagcaguagcgc
uacuccgcccccggaggacugagggggagacggguuccgcggcgccugca
ucuggccgcgggugacucgggccuaagcggcgggugaagaccgggaaggg
gcgugcccgcccgucgaacggggagccggcggagacuccggcaggcgcgg
gcggagacgcgccccccggcgacgcgcacggggaccgcggcgggcggcgc
cccggcccgcgaacgccccgcagcccccggacgccuugcgcggagagggg
ggcccgggggcggaccgcgcguccccggccgccccugaaaagccgggggg
cccgcgcgccguaccgaccgcacaggacuccggggucagcagccucuagc
gcgggagcgaacgcggcucagggaagucggcaagccggcuccguaaccuc
gggaaaaggaguggcucugacggggucagaacuggaacggacgcggggau
cccgacuguuuacuagaaacacagcgucgcgagggccgcacccggcgcug
gcgcgacgugauuucugcccagugccagaccgucaccgugaagcgauccg
ccgaagcccugguaaacggcgggaguaaugacucucuuaagguagccaaa
ugccucgucgggcaauuuccgacggcaugaauggaccaacgaggauccca
cugucccgagccgcgccuccgcgagccuccagccucgggaacgggcgagg
gccggccagcggggcaagaagacccuuuugagcuugacuccagcccgggc
cuguggggcggggccgccccgcucacccggucgcgcggggacccgcccgg
gcggggaguucggcuggggcggcgcgccugcuacaccggaccgcaggcgu
cccacggcgggcucagcgaggacccucccgcggagcagaagggcacaagc
ccgcccgacccgcgccccccgugccggcgcgggccgcgaaagcggggccu
accgauccuucgccgccccggccgcgggcgcggagguggcagaaaaguua
ccacagggauaacuggcuuguggccgccgagcgcccgcagcgacgcggcu
uuuugauccuucgaugucggcucuuccuaccguccgcgcgcaccggcgcg
gaagcgucggauuguucacccguucaagggaucgugagcuggguuuagac
cgucgugagacgguuaguuuuacccuacuggccccggggccagagcacgg
cgggccaguacggaggaacgcccgccgcgggcgcccagccccgcgguugc
ccgccggggcagaccgcgcgcccgggcccgggggccuggcgcugccgccu
cuaaagcgccaccccccccuccggccccgccgcccgcgccccagccccgu
gcccccugcccgaggcggcccccgcccgggaggaccacccggcgcggcgc
cccuguacggcgagggcgcguucgcccggggggcgcgccgcaggcgcg |
......................<<<<<<.....<......>......>>>
>>.>.........<<....>>..<<<<<....<<.....>>.....>>>>
>..[[[...<<<<...........>>>><<<<..<..<<<<<......>>
>>>((......<<<.....))>>>...>>>>>........<<<<<<<...
.....>>>>>>>...(((((..<<<<<<)))))..]]]............
......................<<....>>................<<<.
>>>...........................<<<<<<..>>>>>>.<<<<.
.......>>>>.<<<<<....<<<<<<<<<<<<<..<<<...<<<.>>>.
.>>>...<<....>>............<<<<<<<<<<<<<....>>>>>>
>.>>>>>>...>>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<<
<<<..<<<....<<<<<<<....>>>>>>>.....>>>...<<<..<<.<
<........>>>>.>>>....>>>>>>>>>...<<.......>>......
>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>><<<<<<<<
<<<<<.<<<<<<<<<...<<<...<<<..<<<<..>>>>..>>>..>>.>
...>>>>>>>.<<<<<<<<<<<......>>>>>>>>>>>...>>>>>>>>
>>>>>.>>..<<<<.<<<<<.....>>>>>.>>>>....<<<......>>
>...<<<<<<<..<<<<(((...<<<<<<<.....<<<.<<<<<<<..>>
>>>>>>>>..........)))......>>>>>>>>>>>..>>>>>>><<<
<<<..>>>>>>....>>>>>><.<<<<<<<<...<<......<<<<<.<<
....>>.>>>>>...>>>>>>>>>>..>.....>>>>>.<<.....<<..
..<<<<<....>>>>>..<<.....<<<<..<<...<<<<<<...<....
...>.>>>>>>....((<<<.<<...<<<...<<<....>>>......<<
<<..>>>>...>>.>....>>...<<<<<........>>>>>))<<<<<<
<<<....>>><<<<<<<<<<...<<<..<<<<<<<<<<<<<<<<<.....
....>>>>>....<<<<<<...<<<<<<....<<.....>>......>>>
>>>...>>>>>>..>>>>>.>>>>>>>..>>>.........>>>>>>>>>
>>>>>>>.>>>..>>..<<.....>>.>>>>.<<<<.....>>>>..>>.
...<<<<....<<<<<<<<.<<.........<.....<<<<<....<<..
>>.....>>>>><<.<<<<<<...>>>>>>.>>............<<<<<
<<<<..<<<.........>>>..<<<<<<<....<<<<....>>>>....
..>>>>>>>...<<..<<<..<<<<<<<...<<....<<<.<....>.>>
>....>>.>>>>>..>>>>><<<<<<....>>>>>>........<.....
......<<<<<<.....>>>>>>....>.....>>....>>.>>>>>>>.
.>..>>.>>>>>>>>.>>>>>>....>>....<<<<<........>>>>>
...((((((..{{{.........{{{..{{[[[[..<<<<<.<<<<<<<<
..<<<<<<<<<..>>>>>>>>>...<<<<......>>>>.....>>>>>>
>>..>>>>>...<<<.....>>>..<<<<<<...........>>>>>>..
<<...<<<<<<<...<.<<<<..>>>>.>.....<<...(((>>....>>
>>>>>...<<<<<<<<.........>>>>>>>>.<<<....>>>.>>)))
.......((((((.((((.>>>>>>))))))))))..........]]]].
.}}.}}}.......<<.<.<.<<<<<<...<<.......>>...>>>>>>
...>>.>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>>>
>..>>>.<<<.........>>>....>>>>>..>...>>>.>>....<<<
<<<<....>>>>>>>........}}}.))))))..<<<<<<.<<<..<<<
<<<<<..............>>>>>>>><<<<<...<.<....<<<<<<<<
<<....>>>>>.>>>>>....>.>.>>>>>.<<<...<<<<<<.......
....>>>>>>...>>>..>>>.>>>>>>...<.<<<..............
...............>>>.>...<<.<<<<.......>>>>..<<<<<<<
<<<<....<<<<<<.<..>.>>>>>>...>>>>.>>>>>>>....>>. |
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| PDB | 7pwo Cryo-EM structure of the ancient eukaryotic ribosome from the human parasite Giardia lamblia. |
| Resolution | 2.75 Å |
Binding residue
(original residue number in PDB) | M1 G2 R3 R4 V7 Q8 R9 G11 V15 A18 H19 V20 R23 G25 D33 F34 H50 R54 R67 G70 R71 E118 K119 M121 R123 C125 L126 A127 R128 A129 S130 G131 L150 S152 Q154 R174 K177 L179 K181 A182 G183 H187 K188 R193 W196 P197 V198 V199 R200 G201 V202 A203 M204 N205 V207 D208 H211 G214 N215 H216 G220 V221 S222 S223 C224 P226 R227 N228 V230 P231 G232 Q233 K234 V235 G236 I238 A239 A240 R241 R242 T243 G244 C245 |
Binding residue
(residue number reindexed from 1) | M1 G2 R3 R4 V7 Q8 R9 G11 V15 A18 H19 V20 R23 G25 D33 F34 H50 R54 R67 G70 R71 E118 K119 M121 R123 C125 L126 A127 R128 A129 S130 G131 L150 S152 Q154 R174 K177 L179 K181 A182 G183 H187 K188 R193 W196 P197 V198 V199 R200 G201 V202 A203 M204 N205 V207 D208 H211 G214 N215 H216 G220 V221 S222 S223 C224 P226 R227 N228 V230 P231 G232 Q233 K234 V235 G236 I238 A239 A240 R241 R242 T243 G244 C245 |
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| Enzyme Commision number |
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