Structure of PDB 8ove Chain A1 Binding Site BS01 |
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| >8ove Chain AA (length=1836)
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gaucugguugauucugccaguagucauaugcuuguuucaaggacuuagcc
augcaugccucagaaucacugcgcaggaaucugcgcauggcucauuacau
cagacguaaucugccgccaaaauuuugcgcauuacuggauaacuuggcga
aacgccaagcuaauacaugaaccaaucggacgcucucuuugggacgucca
gcgaaugaaugaaaccaacgccuccggaggcaguaacacucagacguguu
gacucaauucauuccgugcgaaagccgagcugcucggcgucuacugacga
acaacugcccuaucagccagugauggccguguaguggacugccauggcgu
ugacgggagcgggggauuaggguucgauuccggagagggagccugagaaa
uagcuaccacuucuacggagggcagcaggcgcgcaaauugcccaaugucg
aaaaaauacgaugaggcagcgaaaagaaauagagccgaccgugugguugu
uuucaaugggggauacucaaacccauucaauaucgaguaacaauuggagg
acaagucuggugccagcacccgcgguaauuccagcuccaaaagcguauau
uaaugcuguugcuguuaaaggguucguaguugaacugugggccacguagu
guggugccguaccagucccguaccucgacguguuuugacccacgcccucg
uggcccagauacagaaacacgggagcaguucgcaugucaugcaugggcgu
ccgugaauuuuacugugaccaaaaagaugcgaccaaagcaguuugccgac
uugaauuacaaagcaugggauaacgaagcaucagcccugggguuauguug
guuuuagaaguccuugggagauuauggggccgccgcgcggcuucgaauga
aggaggguaguucgggggagaacguacuggugcgucagaggugaaauucu
uagaccgcaccaagacgaacuacagcgaaggcauucuucaaggauaccuu
ccucaaucaagaaccaaaguguggggaucaaagaugauuagagaccauug
uaguccacacugcaaaccaugacacccaugaauuggggagugccucucag
cacguuucuuacuucuucacgcgaaagcuuggagguuacagucucagggg
ggaguacguucgcaagagugaaacuuaaagaaauugacggaauggcacca
caagacguggagcgugcgguuuaauuugacucaacacggggaacuuuacc
agauccggacagggugaggauugacagauggaguucuuucucgauccccu
gaaugguggugcauggccgcuuuuggucgguggagugauuuguuugguug
auuccgucaacggacgagauccaagcugcccaguaggugccgggauuguc
cacacaggacagcauccuucuuuaggccccuucucugcgggauuccuugc
uuuucgcgcaaggugagauuuugggcaacagcaggucugugaugcuccuc
aauguucugggcgacacgcgcacuacaaugucagugagaacaagagucga
cgcucccgcuugaucaaaagagcggggaaaccacggaaucacguagaccc
acuugggaccgaguauugcaauuauuggucgcgcaacgaggaaugucucg
uaggcgcagcucaucaaacugugccgauuacgucccugccauuuguacac
accgcccgucguuguuuccgaugauggugcaauacaggugaucggaccgu
caccgaaaguucaccgauauugcuucaauagaggaagcaaaagucguaac
aagguagcuguaggugaaccugcagcuggaucauuu |
...<<<<<.{.[[[[>>>>><<<<.<<<<<<...<<<...<......<<<
.<<<..<<....<<....<<<..>>>...>>.>>......<<........
<<<..<<..<<...<<..<................<<.....<<<<<<..
...>>>>>>......>>..........<<<<<.<<<.....>>>>>>>>.
<<<<<<<<<<....(((((<<<<....>>>>...................
......>>>>>>>>...>>....<<<<<<<.>>>>>>>...>..>>..>>
>>..>>>.<<<....<<<....<<<<<.<<.......>>.>>>>>>>>..
....>>>..<<<.<<<<....>>>>....>>>.>>.<<.<<<........
..>>>.>>.<<<<<..>>>>>...>>>>>>.........<<<....<<<.
.........>>>..>>>..>....>>>....<<<................
.>>>.......<..............>................<<<<<((
....<.<<<<.....<<..))>>.......>>>>>>>>>>..>>>>>>>>
>>.........<<<[[.....<<<<...<<<.......<<<<...<...<
..<<....<<..<.<.........>.>..>>..>>.>...>..>>>>...
................<<.........<<....<<.......>>..>>..
..>>....<<..<...........<...<<.......>><<<<....>>>
>....>............>..>>...........<<..<<<.<<<.))))
)..>.>>...>>>..>>........<<..<.<.....>>...>>......
....<<<<<..<<...<<<<<<<<..<<<<<<<<...<<<......>>>.
.....>>>>>>>.>.>>.......<<....>>.>>>>>>...>>>>>.>>
....>>>...>>>>...<<<<<<<<...<...<<<<.<.....>.>>>>.
..>>>>>>>>>.........<<<.<<...<..<.<<<<<<<<<......>
>>>.>>>>>.>..>......<<..]]>>.....>>.....>>>.>>>.<<
<......<<<<....>>>>....>>>..]]]].}<<<<<.<<<<<<<..<
<.<<<<<<..<<.<<<<<<<......<<........>>..........<<
<<<.<....<<<<<........<<.<<<......>>>.>>......>>>>
>...<<.<<<..<<.<<<<<<....<<<.<<<<<....>>>...<<<...
...>>>...>>.>>>....<<<<<.<<<<.....<<<.<<<<<<<.....
..................>>>>..>>>.>>>.....>>>>....<<<<<<
.......>>>>>>.......>>>>>....>>>.>>>.....>>>>>>>..
...>.>>>>>...>>.>>>>>.>>.....<<<.<<<.......<....<.
..>.<<<<<<<........>>>>>>>....>........>>>...>>>..
....<....<<<.<<..........>>.>>>.....>.....>>>>>>..
..<<<<<<<.........>>>>>>>......>>...>>>>>>>>>>.>>.
...<..<<.<.<<<<<<<<..<<.<<<.<<<<<<..<<<<<.<...<...
....>...>.>>>>>..>>>>>>.>>>.>>..>>>>>>>>..>.>>...>
.....<<<<<<<<<....>>>>>>>>>......... |
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| PDB | 8ove A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei. |
| Resolution | 2.6 Å |
Binding residue
(original residue number in PDB) | A2 K3 K4 H5 K7 L9 K13 M16 S18 K19 V23 F24 A25 P26 R27 R29 A30 G31 R46 A55 M60 R63 Q64 R74 K78 K103 R105 Y127 T128 G129 T130 G131 R132 H142 R143 R145 R150 R153 L169 I170 K171 K176 G183 H198 G200 V246 R250 |
Binding residue
(residue number reindexed from 1) | A1 K2 K3 H4 K6 L8 K12 M15 S17 K18 V22 F23 A24 P25 R26 R28 A29 G30 R45 A54 M59 R62 Q63 R73 K77 K102 R104 Y126 T127 G128 T129 G130 R131 H141 R142 R144 R149 R152 L168 I169 K170 K175 G182 H197 G199 V245 R249 |
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| Enzyme Commision number |
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