Structure of PDB 7tbl Chain A1 Binding Site BS01

Receptor Information

>7tbl Chain A1 (length=1231) Species: 9606 (Homo sapiens)

ALPPVAKAAQVVNQTLQLDDSYPDLDSYCRPGASSDYEMQSSDSSWAPFH
VVRHHNIPDKVFEHLNAGEVFTKLGLFAEIGYAWASIDSSLFLWDYTHPN
PELIGYEEATHTITAVALVPPKPGVFVKTITHVLVVATTSEIILLGVSAT
PTPSGSKSLTLYSTRMSVHRGGSDVSFIVGTKDGRIFLGGESDTDIHEIF
YQQEERWFSSRCGKINHSHPFGSRQQEWLRGLYVDDTRNLLYSLSNRSTI
RTYHMEGPEKLTKVIEKDKTSCLRDFAHMADSSPLFTDKTNIVALSPIPA
TEASKLHLMALTDTGCRLFLSATSSASYTALAPQSMQLQFVKFPPRESPT
RIRTLSQLDKTSRALDPSALGFRFSPGYFFDVVRKHPNQDMLFVSAPDTG
RIKVTQPASALKYFEQGTWIELENGNRTIEIGLTTAPFAAAKQPLGFGNE
LAVQFDQVPGEFAVLTNTGVHIVRRRRLVDIFAKALGNCVSASDDALERE
VRKFINQYGRVETIAAALAVACGQGSDLMDRNTENLARAAFIEYGGQPRL
ASVRLSSRHDALALYLTRLVRTLWKAKVVQVDISSTIPTSKLVTIQENVE
RLRNFLEANKSTIQGLAPPDIANQKEHQALHALQKLMESISEGISFVLML
FDERVSDIYARLDAVSQQQLKDLTYEQLFSQTPGKELAKVLVKAIVNRNI
ASGANVETVADALRRRCGSFCSPDDVVTFKAQEQLQRASEQAHNSPVLRA
LLAESLRLFEQVAGSLTPANLTTAVEQYISLKYYAGAIQLCLTVAQQKDR
GNTALSWVNDGKPANDSRKKAFDERKICYNLIHQVLDKLESDFAGEPELV
DGRPTLAATKRMEAYNVVNDSSDEVFHFDLYEWYIEKGWTDRILSIDSPH
VITYLQRLAETDFRHAELLCRFYTTRSRFFEAAQVQTNLAKSDLNISLKD
RIILLSRAKGNASVNTIGISRQQQQQLNHEASELLEIAHIQDDLLERLVA
DPRIPEERKAEIEEFLDGPIRTLTDLFNDYADQANYYDLCLLIFHAADFH
NPRTILDTWNNLINQSHFEAEQRREYWPIAEPPLPYVYVSQQIQLIAHRT
SLDSLIFPVNSLLPVVCAYAINNGQDASIGADPCWPIQLFLNLGVPHALV
VQVLENVLDTQEAPFTGRRRKLVVQWIAMAVDMWVREVERRMGSWVSELL
GRADQVLTQIADAEEIASLRRTVKGLKRSVD

Ligand information

>7tbl Chain B1 (length=14) Species: 9606 (Homo sapiens)

RKAKLLPMEEALLP

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7tbl Architecture of the cytoplasmic face of the nuclear pore.
• Resolution: 23.0 Å
• Binding residue (original residue number in PDB): G178 V198 F199 V200 I203 L234 Y235 S236 R238 Q276
• Binding residue (residue number reindexed from 1): G105 V125 F126 V127 I130 L161 Y162 S163 R165 Q203

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sat Nov 23 03:16:48 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '7tbl', asym_id = 'A1', bs = 'BS01', title = 'Architecture of the cytoplasmic face of the nuclear pore.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='7tbl', asym_id='A1', bs='BS01', title='Architecture of the cytoplasmic face of the nuclear pore.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0005643,0006913,0017056', uniprot = '', pdbid = '7tbl', asym_id = 'A1'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0005643,0006913,0017056', uniprot='', pdbid='7tbl', asym_id='A1')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>