Structure of PDB 6x6h Chain A1 Binding Site BS01

Receptor Information
>6x6h Chain A1 (length=242) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
REFTIDFSTQQSYVSSLNSIRTEISTPLEHISQGTTSVSVINHTPPGSYF
AVDIRGLDVYQARFDHLRLIIEQNNLYVAGFVNTATNTFYRFSDFTHISV
PGVTTVSMTTDSSYTTLQRVAALERSGMQISRHSLVSSYLALMEFSGNTM
TRDASRAVLRFVTVTAEALRFRQIQREFRQALSETAPVYTMTPGDVDLTL
NWGRISNVLPEYRGEDGVRVGRISFNNISAILGTVAVILNCH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6x6h Structural basis for the interaction of Shiga toxin 2a with a C-terminal peptide of ribosomal P stalk proteins.
Resolution1.88 Å
Binding residue
(original residue number in PDB)		Q10 V14 R172 Q175 R176 R179 S229
Binding residue
(residue number reindexed from 1)		Q10 V14 R172 Q175 R176 R179 S229
Enzymatic activity
Enzyme Commision number 3.2.2.22: rRNA N-glycosylase.
Gene Ontology
Molecular Function
GO:0030598 rRNA N-glycosylase activity
Biological Process
GO:0017148 negative regulation of translation

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Molecular Function
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Biological Process
External links
PDB RCSB:6x6h, PDBe:6x6h, PDBj:6x6h
PDBsum6x6h
PubMed32878986
UniProtA9ZMR8

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