Structure of PDB 9ciq Chain A Binding Site BS01

Receptor Information
>9ciq Chain A (length=427) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAV
SYEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVM
EIMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGL
PQGPTVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIE
RETGFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKI
RSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGI
EHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKD
RNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKN
CNTSGIQTEWSPPLTMLFLCATKFSAS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9ciq DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
Q38 Y39 W42 S62 W64 K86 P316 K317 T318 I319 G320 C321 S322 K323 N324 P326 G327 R351
Binding residue
(residue number reindexed from 1)
Q38 Y39 W42 S62 W64 K86 P311 K312 T313 I314 G315 C316 S317 K318 N319 P321 G322 R346
External links
PDB RCSB:9ciq, PDBe:9ciq, PDBj:9ciq
PDBsum9ciq
PubMed39259676
UniProtQ9Y253|POLH_HUMAN DNA polymerase eta (Gene Name=POLH)

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