Structure of PDB 9ci9 Chain A Binding Site BS01

Receptor Information
>9ci9 Chain A (length=424) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATGQDRVVALVDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVS
YEARAFGVTRSMWADDAKKLCPDLLLAQVRESRGKANLTKYREASVEVME
IMSRFAVIERASIDEAYVDLTSAVQERLQKLQGQPISADLLPSTYIEGLP
QGVQKEGMRKQGLFQWLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERET
GFQCSAGISHNKVLAKLACGLNKPNRQTLVSHGSVPQLFSQMPIRKIRSL
GGKLGASVIEILGIEYMGELTQFTESQLQSHFGEKNGSWLYAMCRGIEHD
PVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQLAQELEERLTKDRND
NDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNT
SGIQTEWSPPLTMLFLCATKFSAS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9ci9 DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Resolution2.09 Å
Binding residue
(original residue number in PDB)
Q38 Y39 W42 I48 R61 S62 K86 R93 K311 R313 P316 K317 G320 C321 S322 K323 N324 P326 G327
Binding residue
(residue number reindexed from 1)
Q37 Y38 W41 I47 R60 S61 K85 R92 K303 R305 P308 K309 G312 C313 S314 K315 N316 P318 G319
External links
PDB RCSB:9ci9, PDBe:9ci9, PDBj:9ci9
PDBsum9ci9
PubMed39259676
UniProtQ9Y253|POLH_HUMAN DNA polymerase eta (Gene Name=POLH)

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