Structure of PDB 9c9y Chain A Binding Site BS01

Receptor Information
>9c9y Chain A (length=612) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VMKTVLMVAEKPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQP
VRFKMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMV
KFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFR
ARFSSITDTDICNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKY
FQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVNT
DKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPL
ALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISFPRTETTHYPENFD
LKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEA
ELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLS
PGFTEVMPWQSVPLEESLPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAEL
ITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYY
KIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDS
IAGMDELMEVSF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9c9y Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics
Resolution3.35 Å
Binding residue
(original residue number in PDB)		K10 G59 H60 W73 E121 D185 L186 C190 S213 P216 C217 Q218 E326 F336 S513 H517 R524 R561
Binding residue
(residue number reindexed from 1)		K11 G60 H61 W74 E122 D186 L187 C191 S214 P217 C218 Q219 E327 F337 S514 H518 R525 R562
External links
PDB RCSB:9c9y, PDBe:9c9y, PDBj:9c9y
PDBsum9c9y
PubMed
UniProtO95985|TOP3B_HUMAN DNA topoisomerase 3-beta-1 (Gene Name=TOP3B)

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