Structure of PDB 9asq Chain A Binding Site BS01

Receptor Information
>9asq Chain A (length=916) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAK
AARPPWEPDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKARR
TGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVIEY
DDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCVKG
LELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDGGK
EVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIVTN
PGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQKLW
KSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVELSS
QGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCLLQ
LAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGINT
LINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLEEG
GLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMANCF
EALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPNTD
RQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQ
RMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEEL
GMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMNVC
FFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGPSH
ARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKRFI
ERKYRQELKEMRWERE
Ligand information
>9asq Chain C (length=24) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
KPNLHILSKLQEEMKRLAEEREET
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9asq RNAi_protein_f1_SR
Resolution3.0 Å
Binding residue
(original residue number in PDB)		I1114 V1116 E1193 D1233 E1235 Y1236 F1240 V1243
Binding residue
(residue number reindexed from 1)		I670 V672 E749 D789 E791 Y792 F796 V799
External links
PDB RCSB:9asq, PDBe:9asq, PDBj:9asq
PDBsum9asq
PubMed
UniProtQ9NRR4|RNC_HUMAN Ribonuclease 3 (Gene Name=DROSHA)

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