Structure of PDB 9arf Chain A Binding Site BS01

Receptor Information
>9arf Chain A (length=796) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KIVNIGAVLSTRKHEQMFREAVNQANKRIQLQATSVTHKPNAIQMALSVC
EDLISSQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYS
DKSIHLSFLRTVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKR
LETLLEERESKAEKVLQFDPGTKNVTALLMEARELEARVIILSASEDDAA
TVYRAAAMLDMTGSGYVWLVGEREISGNALRYAPDGIIGLQLINGKNESA
HISDAVGVVAQAVHELLEKENITDPPRGCVGNTNIWKTGPLFKRVLMSSK
YADGVTGRVEFNEDGDRKFAQYSIMNLQNRKLVQVGIYNGTHVIPNDRKI
IWPGGETEKPRGYQMSTRLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGD
PVKKVICTGPNDTSPGSPRHTVPQCCYGFCIDLLIKLARTMQFTYEVHLV
ADGKFGTQERVQNSNKKEWNGMMGELLSGQADMIVAPLTINNERAQYIEF
SKPFKYQGLTILVKKEIPRSTLDSFMQPFQSTLWLLVGLSVHVVAVMLYL
LDRFSLTLSSAMWFSWGVLLNSGIGEGAPRSFSARILGMVWAGFAMIIVA
SYTANLAAFLVLDRPEERITGINDPRLRNPSDKFIYATVKQSSVDIYFRR
QVELSTMYRHMEKHNYESAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCD
LVTTGELFFRSGFGIGMRKDSPWKQQVSLSILKSHENGFMEDLDKTWVRY
QECDSRSNAPATLTFENMAGVFMLVAGGIVAGIFLIFIEIAYKRHK
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain9arf Chain A Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9arf Molecular mechanism of ligand-gating in NMDA receptor channel
Resolution3.13 Å
Binding residue
(original residue number in PDB)		F484 T518 W731 D732
Binding residue
(residue number reindexed from 1)		F455 T489 W686 D687
Annotation score4
External links
PDB RCSB:9arf, PDBe:9arf, PDBj:9arf
PDBsum9arf
PubMed
UniProtP35439|NMDZ1_RAT Glutamate receptor ionotropic, NMDA 1 (Gene Name=Grin1)

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