Structure of PDB 8zkc Chain A Binding Site BS01

Receptor Information

>8zkc Chain A (length=346) Species: 562 (Escherichia coli)

KSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAWMDDTLHVELVMPF
VWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPGINGVK
NIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGA
ENQRPTSPDGTHMAPIMSHGLATNSIGYLVWRGPMASKALMQMLQETLWP
DLDYLVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMF
EKVEVPVLGIVENMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMP
LHISLREDLDKGTPTVISRPESEFTAIYRQLADRVAAQLYWQGEVI

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 8zkc Chain A Residue 402

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8zkc Crystal structure of the iron-sulfur cluster transfer protein ApbC from Escherichia coli.
• Resolution: 2.85 Å
• Binding residue (original residue number in PDB): S122 D145 G148 S150
• Binding residue (residue number reindexed from 1): S115 D138 G141 S143
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0005524 ATP binding
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity
• GO:0046872 metal ion binding
• GO:0051536 iron-sulfur cluster binding
• GO:0051539 4 iron, 4 sulfur cluster binding

Biological Process

• GO:0016226 iron-sulfur cluster assembly

Cellular Component

• GO:0005829 cytosol

External links

• PDB: RCSB:8zkc, PDBe:8zkc, PDBj:8zkc
• PDBsum: 8zkc
• PubMed: 38797154
• UniProt: P0AF08|APBC_ECOLI Iron-sulfur cluster carrier protein (Gene Name=mrp)