Structure of PDB 8z9q Chain A Binding Site BS01

Receptor Information
>8z9q Chain A (length=621) Species: 126796 (Thogoto virus (isolate SiAr 126)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDRPDHIDSRVWELSETQEDWITQVHGHVRRVVECWKYTICCLISNMHTH
RGAPQYDVFKWQDRSTIEWICSKKKVQYPERDTPDLYDNERAVAYKVLLV
SDLSDHSPTSGIYHDLAFNLEGEAEESCALVLRGSQLQDIKGFLCRALEW
VVSNNLTQEVVETISGEAKLQFSVGTTFRTLLKRDTDWDVIPTPRVEPNV
PRIEGRRWTQMKKLPLLKEKEGPPSPWRALLLGADSEYIVCPPGTDQEAI
SWIHSQSEIECIRESKSTPASVITCLTSSLQSFAEGNPVRSRIHEDIIAF
GINKKQEKKQSASSSASGEWKRAEYQVEEMSLPPWVEEEMVLLRSDQEDN
WIELEKNAIYTEVDGVAEGLVDKYIEIVGRTKVASVIEKWQIAATRTFSQ
LHTDRSRITACPIITRDPSGNCQFWGMVLLGPHHVKRDTDNAPLLIAEIM
GEDTEEKYPKHSVFSLKVEEKQFLLSLKITSFSRNKLYTFSNIRRVLIQP
ASIYSQVVLSRAAENNSLNLEVNPEIQLYLEGAQRGMTLYQWVRMILCLE
FLMAIYNNPQMEGFLANMRRLHMSRHAMMERRQVFLPFGSRPEDKVNECI
INNPIVAYLAKGWNSMPNVYY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8z9q Cryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses
Resolution2.33 Å
Binding residue
(original residue number in PDB)		S268 G302 K305 K306 K309 Y326 N442 K461 K479 I480 T481 S482 K487
Binding residue
(residue number reindexed from 1)		S267 G301 K304 K305 K308 Y325 N441 K460 K478 I479 T480 S481 K486
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0042025 host cell nucleus
GO:0044423 virion component

View graph for
Cellular Component
External links
PDB RCSB:8z9q, PDBe:8z9q, PDBj:8z9q
PDBsum8z9q
PubMed38816392
UniProtP27194|PA_THOGV Polymerase acidic protein (Gene Name=Segment)

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