Structure of PDB 8yj8 Chain A Binding Site BS01

Receptor Information
>8yj8 Chain A (length=280) Species: 1314 (Streptococcus pyogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDKLKVVATNSIIADMTKAIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKT
SNADVIFYNGINLEDGGQAWFTKLVKNAQKTKNKDYFAVSDGIDVIYLEG
ASEKGKEDPHAWLNLENGIIYSKNIAKQLIAKDPKNKETYEKNLKAYVAK
LEKLDKEAKSKFDAIAENKKLIVTSEGCFKYFSKAYGVPSAYIWEINTEE
EGTPDQISSLIEKLKVIKPSALFVESSVDRRPMETVSKDSGIPIYSEIFT
DSIAKKGKPGDSYYAMMKWNLDKISEGLAK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8yj8 Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8yj8 Characterization of a novel format scFv×VHH single-chain biparatopic antibody against metal binding protein MtsA.
Resolution1.65 Å
Binding residue
(original residue number in PDB)		H52 H124 E190 D265
Binding residue
(residue number reindexed from 1)		H38 H110 E176 D251
Annotation score4
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
Biological Process
GO:0006826 iron ion transport
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8yj8, PDBe:8yj8, PDBj:8yj8
PDBsum8yj8
PubMed38747382
UniProtP0A4G4|MTSA_STRP1 Iron ABC transporter substrate-binding lipoprotein MtsA (Gene Name=mtsA)

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