Structure of PDB 8yha Chain A Binding Site BS01

Receptor Information
>8yha Chain A (length=349) Species: 1852835 (Candidatus Cloacimonetes bacterium ADurb.Bin088) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APPNTLFLRLEGALQSWGSNEAKFALRRTADAPTKSGVLGLLCAAMGIGR
AEAADSWLPKLANLRMGVRIDRPGIRWWDFHTVGAGQRMRMKTRAETLLS
RREYLADASFLVALQGEPELVAKLSAALAKPVWAIYLGRKSCPPSRPVCE
HPPGFYNTLEEALSAVPLQKRWHNEPLPQILPCVMDWIPGYDGEHAPDDA
EIHYDLPVSFQPPRHLPRFVIRRELVVGEDVQVSRETGTSVWRPKGTRAD
YNNSEYKKVRAERLVMDHAACMVCKAPATTVQHVNYRRAGGKEIPEDLRA
LCRLCHDACTMLEYGSGMTTNRIDPCDPIWRERILAKRKEIVEFRSRGQ
Ligand information
>8yha Chain C (length=61) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugaaccggagaagucauuuaauaaggccacuguuaaaaaguauucccca
cgcaugugggg
.............................................<<<<<
<....>>>>>>
Receptor-Ligand Complex Structure
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PDB8yha Mechanisms for HNH-mediated target DNA cleavage in type I CRISPR-Cas systems
Resolution3.4 Å
Binding residue
(original residue number in PDB)		S21 N22 R29 S38 G39 L43 R52 F82 H83 T84 V85 G86 A87 T124 L126 R129 W160 Y163 G165 R166 K167 H242
Binding residue
(residue number reindexed from 1)		S19 N20 R27 S36 G37 L41 R50 F80 H81 T82 V83 G84 A85 T97 L99 R102 W133 Y136 G138 R139 K140 H215
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:8yha, PDBe:8yha, PDBj:8yha
PDBsum8yha
PubMed39047725
UniProtA0A1V6F8C5

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