Structure of PDB 8xri Chain A Binding Site BS01

Receptor Information

>8xri Chain A (length=773) Species: 10498 (African swine fever virus BA71V) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VDVDKYTRARNAGGKRAQDCMLLAAEGDSALSLLRTGLTLGKSNPSGPSF
DFCGMISLGGVIMNACKKVTNIIMVRNEQLTNNKVLQGIVQVLGLDFNCH
YKTQEERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHLFWPQLIIHGFV
KRLLTPLIRVYEKGKTMPVEFYYEQEFDAWAKKQTSLVNHTVKYYKGLAA
HDTHEVKSMFKHFDNMVYTFTLDDSAKELFHIYFGGESELRKRELCTGVV
PLTETQTQSIHSVRRIPCSLHLQVDTKAYKLDAIERQIPNFLDGMTRARR
KILAGGVKCFASNNRERKVFQFGGYVADHMFYHHGDMSLNTSIIKAAQYY
PGSSHLYPVFIGIGSFGSRHLGGKDAGSPRYISVQLASEFIKTMFPAEDS
WLLPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWARQLEDIL
ALVRAYVDKDNPKHELLHYAIKHKITILPLRPSNYNFKGHLKRFGQYYYS
YGTYDISEQRNIITITELPLRVPTVAYIESIKKSSNRMTFIEEIIDYSSS
ETIEILVKLKPNSLNRIVEEFKETEEQDSIENFLRLRNCLHSHLNFVKPK
GGIIEFNSYYEILYAWLPYRRELYQKRLMREHAVLKLRIIMETAIVRYIN
ESAELNLSHYEDEKEASRILSEHGFPPLNHTLIISPEFASIEELNQKALQ
GCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQESPFPGASV
WLEEIDAVEKAIIKGRNTQWKFH

Ligand information

>8xri Chain C (length=28) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gagcagccgagctgcagctcggctgctc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8xri The crystal structure of AsfvTopII in complex with both G-DNA and T-DNA
Resolution	2.92 Å
Binding residue (original residue number in PDB)	K417 E438 G439 D440 S441 G471 G472 V473 N496 D543 R705 Q706 A717 R718 Y751 H753 G754 S757 S761 K764 K793 A850 N851 P852
Binding residue (residue number reindexed from 1)	K5 E26 G27 D28 S29 G59 G60 V61 N77 D124 R286 Q287 A298 R299 Y332 H334 G335 S338 S342 K345 K374 A431 N432 P433

External links

PDB	RCSB:8xri, PDBe:8xri, PDBj:8xri
PDBsum	8xri
PubMed
UniProt	Q00942\|TOP2_ASFB7 DNA topoisomerase 2 (Gene Name=TOP)

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