Structure of PDB 8xrf Chain A Binding Site BS01

Receptor Information

>8xrf Chain A (length=773) Species: 10498 (African swine fever virus BA71V) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VDVDKYTRARNAGGKRAQDCMLLAAEGDSALSLLRTGLTLGKSNPSGPSF
DFCGMISLGGVIMNACKKVTNITTIMVRNEQLTNNKVLQGIVQVLGLDFN
CHYKTQEERAKLRYGCIVACVDQDLDGCGKILGLLLAYFHLFWPQLIIHG
FVKRLLTPLIRVYEKGKTMPVEFYYEQEFDAWAKKQTSLVNHTVKYYKGL
AAHDTHEVKSMFKHFDNMVYTFTLDDSAKELFHIYFGGESELRKRELCTG
VVPLTETQTQSIHSVRRIPCSLHLQVDTKAYKLDAIERQIPNFLDGMTRA
RRKILAGGVKCFASNNRERKVFQFGGYVADHMFYHHGDMSLNTSIIKAAQ
YYPGSSHLYPVFIGIGSFGSRHLGGKDAGSPRYISVQLASEFIKTMFPAE
DSWLLPYVFEDGQRAEPEYYVPVLPLAIMEYGANPSEGWKYTTWARQLED
ILALVRAYVDKDNPKHELLHYAIKHKITILPLRPSNYNFKGHLKRFGQYY
YSYGTYDISEQRNIITITELPLRVPTVAYIESIKKSSNRMTFIEEIIDYS
SSETIEILVKLPNSLNRIVEEFKETEEQDSIENFLRLRNCLHSHLNFVKP
KGGIIEFNSYYEILYAWLPYRRELYQKRLMREHAVLKLRIIMETAIVRYI
NESAELNLSHYEDEKEASRILSEHGFPPLNHTLIISPEFASIEELNQKAL
QGCYTYILSLQARELLIAAKTRRVEKIKKMQARLDKVEQLLQESPFPGAS
VWLEEIDAVEKAIIKGRNTQWKF

Ligand information

>8xrf Chain C (length=10) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gatgacgatt

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8xrf The crystal structure of AsfvTopII in complex with G-DNA
Resolution	2.94 Å
Binding residue (original residue number in PDB)	E438 G472 V473 D543 R705 Q706 T715 R718 Y751 H753 G754 S757 S761 K764 K793 N851 P852
Binding residue (residue number reindexed from 1)	E26 G60 V61 D126 R288 Q289 T298 R301 Y334 H336 G337 S340 S344 K347 K376 N434 P435

External links

PDB	RCSB:8xrf, PDBe:8xrf, PDBj:8xrf
PDBsum	8xrf
PubMed
UniProt	Q00942\|TOP2_ASFB7 DNA topoisomerase 2 (Gene Name=TOP)

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