Structure of PDB 8xiq Chain A Binding Site BS01

Receptor Information
>8xiq Chain A (length=289) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LAVSGVLIPLVYLVVCVVGLLGNSLVIYVVLRHTASPSVTNVYILNLALA
DELFMLGLPFLAAQNALSYWPFGSLMCRLVMAVDGINQFTSIFCLTVMSV
DRYLAVVHPTRSARWRTAPVARTVSAAVWVASAVVVLPVVVFSGVPRGMS
TCHMQWPEPAAAWRAGFIIYTAALGFFGPLLVICLCYLLIVVKVRSAGRR
VWAPSCQRRRRSERRVTRMVVAVVALFVLCWMPFYVLNIVNVVCPLPEEP
AFFGLYFLVVALPYANSCANPILYGFLSYRFKQGFRRVL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8xiq Selective ligand recognition and activation of somatostatin receptors SSTR1 and SSTR3
Resolution2.71 Å
Binding residue
(original residue number in PDB)
F99 L100 Q103 V119 M120 D123 G124 M193 F206 F273
Binding residue
(residue number reindexed from 1)
F60 L61 Q64 V80 M81 D84 G85 M154 F167 F234
External links
PDB RCSB:8xiq, PDBe:8xiq, PDBj:8xiq
PDBsum8xiq
PubMed
UniProtP32745|SSR3_HUMAN Somatostatin receptor type 3 (Gene Name=SSTR3)

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