Structure of PDB 8x5v Chain A Binding Site BS01

Receptor Information
>8x5v Chain A (length=892) Species: 1465 (Brevibacillus laterosporus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MAYTMGIDVGIASCGWAIVDLERQRIIDIGVRTFEEALAVPRREARSSRR
RLRRKKHRIERLKHMFVRNGLAVDIQHLEQTLRSQNEIDVWQLRVDGLDR
MLTQKEWLRVLIHLAQRRGFQSNRKTEDGQVLVNVTENDRLMEEKDYRTV
AEMMVKDEKFSDHKRNKNGNYHGVVSRSSLLVEIHTLFETQRQHHNSLAS
KDFELEYVNIWSAQRPVATKDQIEKMIGTCTFLPKEKRAPKASWHFQYFM
LLQTINHIRITNVQGTRSLNKEEIEQVVNMALTKSKVSYHDTRKILDLSE
EYQFVGLDYGKEDEKKKVESKETIIKLDDYHKLNKIFNEVELAKGETWEA
DDYDTVAYALTFFKDDEDIRDYLQNKYKDSKNRLVKNLANKEYTNELIGK
VSTLSFRKVGHLSLKALRKIIPFLEQGMTYDKACQAAGFDFQGISKKKRS
VVLPVIDQISNPVVNRALTQTRKVINALIKKYGSPETIHIETGGGSGGYI
TKYLSHFISTNLEFSPSDKKKKVVNTSGRITSHLRSRWGLENDLHHAMDA
IVIAVTSDSFIQQVTNYYKRKERFPLPWKFFREEVIARLSPNPKEQIEAL
PNHFYSEDELADLQPIFVSRMPKRSITGEAHQAQFRRVVGKTKEGKNITA
KKTALVDISYDKNGDFNMYGRETDPATYEAIKERYLEFGGNVKKAFSTDL
HKPKKDGTKGPLIKSVRIMENKTLVHPVNKGKGVVYNSSIVRTDVFQRKE
KYYLLPVYVTDVTKGKLPNKVIVAKKGYHDWIEVDDSFTFLFSLYPNDLI
FIRQNPKKKISLKKRIESHSISDSKEVQEIHAYYKGVDSSTAAIEFIIHD
GSYYAKGVGVQNLDCFEKYQVDILGNYFKVKGEKRLELETSD
Ligand information
>8x5v Chain B (length=106) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggaaauuaggugcgcuuggcgcuauaguuccuugaaaaaguugcuauagu
aagggcgacccgaggcguuggggaucgccuagcccguuuuuacgggcucu
ccccau
....................<<<<<<<<..<<<....>>>..>>>>>>>>
..<<<...>>>..((((..<<<<<.)))).<<<<<<<....>>>>>>>.>
>>>>..
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8x5v Structure and engineering of Brevibacillus laterosporus Cas9.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		A45 L46 A47 R50 R51 A53 R54 R57 R58 R59 L60 R61 R62 K64 H65 R69 Q93 D97 V98 W99 H121 Q124 R125 R126 G127 D174 K176 R177 N178 K179 V186 R189 Q226 R227 V229 T243 L245 P246 K247 E248 K253 F258 F261 M262 Q265 H423 K427 Y442 F453 Q454 K458 K459 K460 Q470 S472 N473 P474 N477 R478 T481 K485 K492 R808 S809 I810 G812 E813 A814 H815 Q818 F819 R821 K835 K836 Y853 E856 T857 D858 K886 K888 K889 P895 L896 K898 S899 R901 N913 K916 T947 Q1054 I1057 F1062 K1065 G1066 L1070 E1071 L1072 E1073 D1076
Binding residue
(residue number reindexed from 1)		A37 L38 A39 R42 R43 A45 R46 R49 R50 R51 L52 R53 R54 K56 H57 R61 Q85 D89 V90 W91 H113 Q116 R117 R118 G119 D162 K164 R165 N166 K167 V174 R177 Q214 R215 V217 T231 L233 P234 K235 E236 K241 F246 F249 M250 Q253 H411 K415 Y430 F441 Q442 K446 K447 K448 Q458 S460 N461 P462 N465 R466 T469 K473 K480 R624 S625 I626 G628 E629 A630 H631 Q634 F635 R637 K651 K652 Y669 E672 T673 D674 K702 K704 K705 P711 L712 K714 S715 R717 N729 K732 T763 Q870 I873 F878 K881 G882 L886 E887 L888 E889 D892
External links