Structure of PDB 8wzt Chain A Binding Site BS01

Receptor Information

>8wzt Chain A (length=129) Species: 9031 (Gallus gallus)

KVFGRCELAAAMKRHGLDNYRGYSLGNWVCAAKFESNFNTQATNRNTDGS
TDYGILQINSRWWCNDGRTPGSRNLCNIPCSALLSSDITASVNCAKKIVS
DGNGMNAWVAWRNRCKGTDVQAWIRGCRL

Ligand information

• Ligand ID: XTX
• InChI: InChI=1S/3CO.Mn/c3*1-2;
• InChIKey: POELCWUFOUTELL-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.385: [Mn].[C-]#[O+].[C-]#[O+].[C-]#[O+]
  OpenEye OEToolkits 2.0.7: C(#O)[Mn](C#O)C#O
• Formula: C3 Mn O3
• Name: tris($l^{3}-oxidanylidynemethyl)manganese
• PDB chain: 8wzt Chain A Residue 203

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8wzt Real-time observation of a metal complex-driven reaction intermediate using a porous protein crystal and serial femtosecond crystallography.
• Resolution: 1.6 Å
• Binding residue (original residue number in PDB): A11 H15 I88
• Binding residue (residue number reindexed from 1): A11 H15 I88
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0003796 lysozyme activity
• GO:0005515 protein binding
• GO:0016231 beta-N-acetylglucosaminidase activity
• GO:0016798 hydrolase activity, acting on glycosyl bonds
• GO:0042802 identical protein binding

Biological Process

• GO:0016998 cell wall macromolecule catabolic process
• GO:0031640 killing of cells of another organism
• GO:0042742 defense response to bacterium
• GO:0050829 defense response to Gram-negative bacterium
• GO:0050830 defense response to Gram-positive bacterium

Cellular Component

• GO:0005576 extracellular region
• GO:0005615 extracellular space
• GO:0005737 cytoplasm
• GO:0005783 endoplasmic reticulum

External links

• PDB: RCSB:8wzt, PDBe:8wzt, PDBj:8wzt
• PDBsum: 8wzt
• PubMed: 38951539
• UniProt: P00698|LYSC_CHICK Lysozyme C (Gene Name=LYZ)