Structure of PDB 8wyy Chain A Binding Site BS01

Receptor Information
>8wyy Chain A (length=1069) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IHEKSPKHNSYDIIEKRYNEEFKMTYTVYQHKKAKTQVISLGTNDPLDVE
QAFAFYVKTLTHSGKGIPHILEHSVLSGSKNYNYKNSIGLLEKGTLHTHL
NAYTFNDRTVYMAGSMNNKDFFNIMGVYMDSVFQPNVLENKYIFETEGWT
YEVEKLKEDEKGKAEIPQMKDYKVSFNGIVYNEMKGALSSPLEDLYHEEM
KYMFPDNVHSNNSGGDPKEITNLTYEEFKEFYYKNYNPKKVKVFFFSKNN
PTELLNFVDQYLGQLDYSKYRDDAVESVEYQTYKKGPFYIKKKYGDHSEE
KENLVSVAWLLNPKVDLSLENPTDYFVLLIINNLLIHTPESVLYKALTDC
GLGNNVIDRGLNDSLVQYIFSIGLKGIKRNNEKIKNFDKVHYEVEDVIMN
ALKKVVKEGFNKSAVEASINNIEFILKEANLKTSKSIDFVFEMTSKLNYN
RDPLLIFEFEKYLNIVKNKIKNEPMYLEKFVEKHFINNAHRSVILLEGDE
NYAQEQENLEKQELKKRIENFNEQEKEQVIKNFEELSKYKNAEESPEHLN
KFPIISISDLNKKTLEVPVNVYFTNINENNNIMETYNKLKTNEHMLKDNM
DVFLKKYVLKYEGNVPILVYEMPTTGIVYLQFVFSLDHLTVDELAYLNLF
KTLILENKTNKRSSEDFVILREKNIGSMSANVALYSKDDHLNVTDKYNAQ
ALFNLEMHVLSHKCNDALNIALEAVKESDFSNKKKVIDILKRKINGMKTT
FSEKGYAILMKYVKAHLNSKHYAHNIIYGYENYLKLQEQLELAENDFKTL
ENILVRIRNKIFNKKNLMVSVTSDYGALKHLFVNSNESLKNLVSYFEEND
KYIMGWNEEIKSKKLFDEEKVKKEFFVLPTFVNSVSMSGILFKPGEYLDP
SFTVIVAALKNSYLWDTVRGLNGAYGVFADIEYDGSVVFLSARDPNLEKT
LATFRESAKGLRKMADTMTENDLLRYIINTIGTIDKPRRGIELSKLSFLR
LISNESEQDRVEFRKRIMNTKKEDFYKFADLLESKVNEFEKNIVIITTKE
KANEYIANVDGEFKKVLIE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8wyy Chain A Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8wyy Open falcilysin, from free falcilysin dataset
Resolution3.1 Å
Binding residue
(original residue number in PDB)		H129 H133 E243
Binding residue
(residue number reindexed from 1)		H69 H73 E183
Annotation score4
External links
PDB RCSB:8wyy, PDBe:8wyy, PDBj:8wyy
PDBsum8wyy
PubMed
UniProtQ76NL8|FCLN_PLAF7 Falcilysin (Gene Name=FLN)

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