Structure of PDB 8wyx Chain A Binding Site BS01

Receptor Information
>8wyx Chain A (length=1070) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EWIHEKSPKHNSYDIIEKRYNEEFKMTYTVYQHKKAKTQVISLGTNDPLD
VEQAFAFYVKTLTHSGKGIPHILEHSVLSGSKNYNYKNSIGLLEKGTLHT
HLNAYTFNDRTVYMAGSMNNKDFFNIMGVYMDSVFQPNVLENKYIFETEG
WTYEVEKLKEDEKGKAEIPQMKDYKVSFNGIVYNEMKGALSSPLEDLYHE
EMKYMFPDNVHSNNSGGDPKEITNLTYEEFKEFYYKNYNPKKVKVFFFSK
NNPTELLNFVDQYLGQLDYSKYRDDAVESVEYQTYKKGPFYIKKKYGDHS
EEKENLVSVAWLLNPKVDLSLENPTDYFVLLIINNLLIHTPESVLYKALT
DCGLGNNVIDRGLNDSLVQYIFSIGLKGIKRNNEKIKNFDKVHYEVEDVI
MNALKKVVKEGFNKSAVEASINNIEFILKEANLKTSKSIDFVFEMTSKLN
YNRDPLLIFEFEKYLNIVKNKIKNEPMYLEKFVEKHFINNAHRSVILLEG
DENYAQEQENLEKQELKKRIENFNEQEKEQVIKNFEELSKYKNAEESPEH
LNKFPIISISDLNKKTLEVPVNVYFTNINENNNIMETYNKLKTNEHMLKD
NMDVFLKKYVLKYEGNVPILVYEMPTTGIVYLQFVFSLDHLTVDELAYLN
LFKTLILENKTNKRSSEDFVILREKNIGSMSANVALYSKDDHLNVTDKYN
AQALFNLEMHVLSHKCNDALNIALEAVKESDFSNKKKVIDILKRKINGMK
TTFSEKGYAILMKYVKAHLNSKHYAHNIIYGYENYLKLQEQLELAENDFK
TLENILVRIRNKIFNKKNLMVSVTSDYGALKHLFVNSNESLKNLVSYFEE
NDKYIMGWNEEIKSKKLFDEEKVKKEFFVLPTFVNSVSMSGILFKPGEYL
DPSFTVIVAALKNSYLWDTVRGLNGAYGVFADIEYDGSVVFLSARDPNLE
KTLATFRESAKGLRKMADTMTENDLLRYIINTIGTIDKPRRGIELSKLSF
LRLISNESEQDRVEFRKRIMNTKKEDFYKFADLLESKVNEFEKNIVIITT
KEKANEYIANVDGEFKKVLI
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain8wyx Chain A Residue 1201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB8wyx Partially closed falcilysin, from free falcilysin dataset
Resolution3.5 Å
Binding residue
(original residue number in PDB)		H129 H133 E243
Binding residue
(residue number reindexed from 1)		H71 H75 E185
Annotation score4
External links
PDB RCSB:8wyx, PDBe:8wyx, PDBj:8wyx
PDBsum8wyx
PubMed
UniProtQ76NL8|FCLN_PLAF7 Falcilysin (Gene Name=FLN)

[Back to BioLiP]