Structure of PDB 8wo8 Chain A Binding Site BS01

Receptor Information
>8wo8 Chain A (length=463) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEIAVRIRGIYSTALTKLLMDRGFKIVQPSDVIAERFGIEKSYEDFDVDI
YDKNHGVTIVGTKVEAVKKVFEEEFIDVFFRKLPYKLHGIYKGLVVKRDD
RFVYVDIGNVIGTVLIEELPDAAEGDEVVVQVKKHNVLPHLSTLITIPGD
YAVLIPKPVQRHVKISRKIKDPEERERLRILGLSVDLGEWGVLWRTAAAY
KDWNTLRDELVRLSKIADKLKEAEKFSAPAEIIEGREIYEIEFGGGVKKK
LDEIRNEVVPTIEGHHQFKSYDPEFTLAVDVAEGILAKLPSQRQKISKGF
LEAIITSKGPKVGWIFTLNHVKPDGQIIKIGPGEVIEVSTDPLKVTIKRY
LRPGKFYDGLEVPIESGDYAITEIEAGKWWFVHRYYDKDGNLKGEFYNIN
TPVEIYPDKARYVDLEVDIVRWPDGKKEIIDKEKLKEHYEEGIISEKLYK
ATLRIAQEVYDRL
Ligand information
Receptor-Ligand Complex Structure
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PDB8wo8 Homo-trimeric structure of the ribonuclease for rRNA processing, FAU-1, from Pyrococcus furiosus.
Resolution2.78 Å
Binding residue
(original residue number in PDB)		R10 H92 P152 K170 S172 R173 K174 L199 R201 T202
Binding residue
(residue number reindexed from 1)		R6 H88 P148 K164 S166 R167 K168 L193 R195 T196
Enzymatic activity
Enzyme Commision number 3.1.26.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters
GO:0035925 mRNA 3'-UTR AU-rich region binding
Biological Process
GO:0006364 rRNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:8wo8, PDBe:8wo8, PDBj:8wo8
PDBsum8wo8
PubMed38302756
UniProtQ8U4Q7|FAU1_PYRFU Probable ribonuclease FAU-1 (Gene Name=fau-1)

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