Structure of PDB 8wg5 Chain A Binding Site BS01

Receptor Information
>8wg5 Chain A (length=98) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
Ligand information
>8wg5 Chain I (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acaggatgtatatatctgacacgtgcctggagactagggagtaatcccct
tggcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgcta
gagctgtctacgaccaattgagcggcctcggcaccgggattctccag
Receptor-Ligand Complex Structure
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PDB8wg5 Cryo-EM structure of USP16 bound to H2AK119Ub nucleosome
Resolution3.05 Å
Binding residue
(original residue number in PDB)
Y41 R42 T45 R72 R83 F84 Q85 R116
Binding residue
(residue number reindexed from 1)
Y5 R6 T9 R36 R47 F48 Q49 R80
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8wg5, PDBe:8wg5, PDBj:8wg5
PDBsum8wg5
PubMed38918638
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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