Structure of PDB 8w21 Chain A Binding Site BS01

Receptor Information
>8w21 Chain A (length=417) Species: 272561 (Chlamydia trachomatis D/UW-3/CX) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVVISDIEAREILDSRGYPTLCVKVITNTGTFGEACVPSGAKEALELRDK
DPKRYQGKGVLQAISNVEKVLVPALQGFSVFDQITADAIMIDADGTPNKE
KLGANAILGVSLALAKAAANTLQRPLYRYLGGSFSHVLPCPMMNLINGGM
HATNGLQFQEFMIRPISAPSLKEAVRMGAEVFNALKKILQNRQLATGVGD
EGGFAPNLASNAEALDLLLTAIETAGFTPREDISLALDCAASSFYNTQDK
TYDGKSYADQVGILAELCEHYPIDSIEDGLAEEDFEGWKLLSETLGDRVQ
LVGDDLFVTNSALIAEGIAQGLANAVLIKPNQIGTLTETAEAIRLATIQG
YATILSHRSGETEDTTIADLAVAFNTGQIKTGSLSRSERIAKYNRLMAIE
EEMGPEALFQDSNPFSK
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8w21 Chain A Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8w21 Crystal Structure of Enolase from Chlamydia trachomatis (P43212 Form)
Resolution2.25 Å
Binding residue
(original residue number in PDB)		D244 E283 D310
Binding residue
(residue number reindexed from 1)		D238 E277 D304
Annotation score1
Enzymatic activity
Enzyme Commision number 4.2.1.11: phosphopyruvate hydratase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006096 glycolytic process
Cellular Component
GO:0000015 phosphopyruvate hydratase complex
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0009986 cell surface

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8w21, PDBe:8w21, PDBj:8w21
PDBsum8w21
PubMed
UniProtO84591|ENO_CHLTR Enolase (Gene Name=eno)

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