Structure of PDB 8vme Chain A Binding Site BS01

Receptor Information
>8vme Chain A (length=357) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QMKVSRDSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCD
SGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEKKDEVY
LNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGI
CHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPEL
IFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPT
REQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTA
RLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATIL
IPPHARH
Ligand information
>8vme Chain B (length=20) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
LVEPQKFAEELIHRLEAVQR
Receptor-Ligand Complex Structure
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PDB8vme Structural and functional effects of phosphopriming and scaffolding in the kinase GSK-3 beta.
Resolution2.3 Å
Binding residue
(original residue number in PDB)
V263 D264 L266 Y288 F291 F293 P294
Binding residue
(residue number reindexed from 1)
V236 D237 L239 Y261 F264 F266 P267
External links
PDB RCSB:8vme, PDBe:8vme, PDBj:8vme
PDBsum8vme
PubMed39226374
UniProtQ9WV60|GSK3B_MOUSE Glycogen synthase kinase-3 beta (Gene Name=Gsk3b)

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