Structure of PDB 8vjp Chain A Binding Site BS01

Receptor Information
>8vjp Chain A (length=152) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQ
RNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFG
AFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHV
ED
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8vjp Histidine-Covalent Stapled Alpha-Helical Peptides Targeting hMcl-1.
Resolution1.13 Å
Binding residue
(original residue number in PDB)		V220 H224 M231 H252 V253 D256 G262 R263 T266
Binding residue
(residue number reindexed from 1)		V49 H53 M60 H81 V82 D85 G91 R92 T95
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:8vjp, PDBe:8vjp, PDBj:8vjp
PDBsum8vjp
PubMed38695666
UniProtQ07820|MCL1_HUMAN Induced myeloid leukemia cell differentiation protein Mcl-1 (Gene Name=MCL1)

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