Structure of PDB 8ve8 Chain A Binding Site BS01

Receptor Information
>8ve8 Chain A (length=191) Species: 11622 (Lassa virus Josiah) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLYKGVYELQTLELNMETLNMTMPLSCTKNNSHHYIMVGNETGLELTLTN
TSIINHKFCNLSDAHKKNLYDHALMSIISTFHLSIPNFNQYEAMSCDFNG
GKISVQYNLSHCGTVANGVLQTFMRMAWGGSYIALDSGCGNWDCIMTSYQ
YLIIQNTTWEDHCQFSRPSPIGYLGLLSQRTRDIYISRRLL
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain8ve8 Chain V Residue 4 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ve8 Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		D229 C231
Binding residue
(residue number reindexed from 1)		D161 C163
Annotation score4
External links
PDB RCSB:8ve8, PDBe:8ve8, PDBj:8ve8
PDBsum8ve8
PubMed39243373
UniProtP08669|GLYC_LASSJ Pre-glycoprotein polyprotein GP complex (Gene Name=GPC)

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