Structure of PDB 8v3p Chain A Binding Site BS01

Receptor Information

>8v3p Chain A (length=462) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ELRCGGLLFSSRFDSGNLAHVEKVESLSSPDYEFNVWTRPDCAETEFENG
NRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE
RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQ
LDQRFPENHPTHSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDR
EPRLEQLFPDTSTPRPFRFAGKRIFFLSSRVHPGETPSSFVFNGFLDFIL
RPDDPRAQTLRRLFVFKLIPMLNPDGVVRGHYRTDSRGVNLNRQYLKPDA
VLHPAIYGAKAVLLYHHVSGGSGVAYYVDLHGHASKRGCFMYGNSFSDES
TQVENMLYPKLISLNSAHFDFQGCNFSEKNMYARQSKEGSGRVAIYKASG
IIHSYTLACNYNTYTVELFEQVGRAMAIAALDMAECNPWPRIVLSSLTNL
RAWMLKHVRNSR

Ligand information

>8v3p Chain I (length=1) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8v3p Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
Resolution	2.36 Å
Binding residue (original residue number in PDB)	E255 R303 R313 G435 H436 A437 Y445 K495 R500 T514
Binding residue (residue number reindexed from 1)	E235 R283 R293 G332 H333 A334 Y342 K387 R392 T406

External links

PDB	RCSB:8v3p, PDBe:8v3p, PDBj:8v3p
PDBsum	8v3p
PubMed	39020174
UniProt	Q8NDL9\|CBPC5_HUMAN Cytosolic carboxypeptidase-like protein 5 (Gene Name=AGBL5)

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