Structure of PDB 8v3o Chain A Binding Site BS01

Receptor Information

>8v3o Chain A (length=471) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ELRCGGLLFSSRFDSGNLAHVEKVESLSSPDYEFNVWTRPDCAETEFENG
NRSWFYFSVRGGMPGKLIKINIMNMNKQSKLYSQGMAPFVRTLPTRPRWE
RIRDRPTFEMTETQFVLSFVHRFVEGRGATTFFAFCYPFSYSDCQELLNQ
LDQRFPENHPTHSSPLDTIYYHRELLCYSLDGLRVDLLTITSCHGLREDR
EPRLEQLFPDTSTPRPFRFAGKRIFFLSSRVHPGETPSSFVFNGFLDFIL
RPDDPRAQTLRRLFVFKLIPMLNPDGVVRGHYRTDSRGVNLNRQYLKPDA
VLHPAIYGAKAVLLYHHVSGSGSGVAYYVDLHGHASKRGCFMYGNSFSDE
STQVENMLYPKLISLNSAHFDFQGCNFSEKNMYARDRRDGQSKEGSGRVA
IYKASGIIHSYTLACNYNTGTVELFEQVGRAMAIAALDMAECNPWPRIVL
SEHSSLTNLRAWMLKHVRNSR

Ligand information

>8v3o Chain I (length=7) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

EEGEDEA

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8v3o Tubulin code eraser CCP5 binds branch glutamates by substrate deformation.
Resolution	2.3 Å
Binding residue (original residue number in PDB)	K97 Q98 S99 K100 H252 E255 Y302 R303 R313 H434 G435 H436 A437 S438 K495 R500 T514
Binding residue (residue number reindexed from 1)	K77 Q78 S79 K80 H232 E235 Y282 R283 R293 H332 G333 H334 A335 S336 K393 R398 T412

External links

PDB	RCSB:8v3o, PDBe:8v3o, PDBj:8v3o
PDBsum	8v3o
PubMed	39020174
UniProt	Q8NDL9\|CBPC5_HUMAN Cytosolic carboxypeptidase-like protein 5 (Gene Name=AGBL5)

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