Structure of PDB 8v1r Chain A Binding Site BS01

Receptor Information
>8v1r Chain A (length=1087) Species: 10306 (Human alphaherpesvirus 1 strain KOS) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPTQRHTYYSECDEFRFIAPRVLDEDAPPEKRAGVHDGHLKRAPKVYCGG
DERDVLRVGSGGFWPRRSRLWGGVDHAPAGFNPTVTVFHVYDILENVEHA
YGMRAAQFHARFMDAITPTGTVITLLGLTPEGHRVAVHVYGTRQYFYMNK
EEVDRHLQCRAPRDLCERMAAALRESPGASFRGISADHFEAEVVERTDVY
YYETRPALFYRVYVRSGRVLSYLCDNFCPAIKKYEGGVDATTRFILDNPG
FVTFGWYRLKPGRNNTLAQPRAPMAFGTSSDVEFNCTADNLAIEGGMSDL
PAYKLMCFDIECKAGGEDELAFPVAGHPEDLVIQISCLLYDLSTTALEHV
LLFSLGSCDLPESHLNELAARGLPTPVVLEFDSEFEMLLAFMTLVKQYGP
EFVTGYNIINFDWPFLLAKLTDIYKVPLDGYGRMNGRGVFRVWDIGQSHF
QKRSKIKVNGMVNIDMYGIITDKIKLSSYKLNAVAEAVLKDKKKDLSYRD
IPAYYATGPAQRGVIGEYCIQDSLLVGQLFFKFLPHLELSAVARLAGINI
TRTIYDGQQIRVFTCLLRLADQKGFILPDTQGRFRGRHVGYQGARVLDPT
SGFHVNPVVVFDFASLYPSIIQAHNLCFSTLSLRADAVAHLEAGKDYLEI
EVGGRRLFFVKAHVRESLLSILLRDWLAMRKQIRSRIPQSSPEEAVLLDK
QQAAIKVVCNSVYGFTGVQHGLLPCLHVAATVTTIGREMLLATREYVHAR
WAAFEQLLADFPEAADMRAPGPYSMRIIYGDTDSIFVLCRGLTAAGLTAM
GDKMASHISRALFLPPIKLECEKTFTKLLLIAKKKYIGVIYGGKMLIKGV
DLVRKNNCAFINRTSRALVDLLFYDDTVSGAAAALAERPAEEWLARPLPE
GLQAFGAVLVDAHRRITDPERDIQDFVLTAELSRHPRAYTNKRLAHLTVY
YKLMARRAQVPSIKDRIPYVIVAQTREVEETVARLARKLLVSELAEDPAY
AIAHGVALNTDYYFSHLLGAACVTFKALFGNNAKITESLLKRFIPEVWHP
PDDVAARLRAAGFGAVGAGATAEETRRMLHRAFDTLA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8v1r Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
K534 R692 D886 T887 K939 Y941 K953 G954 R959 K960 N961 E1036 R1039 Y1044 T1045 N1046 H1051 R1071
Binding residue
(residue number reindexed from 1)
K475 R587 D781 T782 K834 Y836 K848 G849 R854 K855 N856 E931 R934 Y939 T940 N941 H946 R966
External links