Structure of PDB 8uza Chain A Binding Site BS01 |
| >8uza Chain A (length=910) Species: 1422 (Geobacillus stearothermophilus)
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MRYKIGLAIGITSVGWAVMNLDIPRIEDLGVRIFDRAENPQTGESLALPR
RLARSARRRLRRRKHRLERIRRLVIREGILTKEELDKLFEEKHEIDVWQL
RVEALDRKLNNDELARVLLHLAKRRGFKSNRKSSTMLKHIEENRAILSSY
RTVGEMIVKDPKFALHKRNKGENYTNTIARDDLEREIRLIFSKQREFGNM
SCTEEFENEYITIWASQRPVASKDDIEKKVGFCTFEPKEKRAPKATYTFQ
SFIAWEHINKLRLISPSGARGLTDEERRLLYEQAFQKNKITYHDIRTLLH
LPDDTYFKGIVYDRGESRKQNENIRFLELDAYHQIRKAVDKVYGKGKSSS
FLPIDFDTFGYALTLFKDDADIHSYLRNEYEQNGKRMPNLANKVYDNELI
EELLNLSFTKFGHLSLKALRSILPYMEQGEVYSSACERAGYTFTGPKKKQ
KTMLLPNIPPIANPVVMRALTQARKVVNAIIKKYGSPVSIHIELARDLSQ
TFDERRKTKKEQDENRTRYISRFFANFIREHLKFAESDDKQKVYTVNGRV
TAHLRSRWEFNKNREESDLHHAVDAVIVACTTPSDIAKVTAFYQRREQNE
PHFPQPWPHFADELRARLSKHPKESIKALNLGNYDDQKLESLQPVFVSRM
PKRSVTGAAHQETLRRYVGIDERSGKIQTVVKTKLSEIKLDASGHFPMYG
KESDPRTYEAIRQRLLEHNNDPKKAFQEPLYKPKKNGEPGPVIRTVKIID
TKNQVIPLNDGKTVAYNSNIVRVDVFEKDGKYYCVPVYTMDIMKGILPNK
AIEPNKPYSEWKEMTEDYTFRFSLYPNDLIRIELPREKTVKTAAGEEINV
KDVFVYYKTIDSANGGLELISHDHRFSLRGVGSRTLKRFEKYQVDVLGNI
YKVRGEKRVG |
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| PDB | 8uza Accelerated DNA unwinding supercharges genome editing by engineered CRISPR-Cas9 |
| Resolution | 3.17 Å |
Binding residue
(original residue number in PDB) | S45 L46 R50 R51 R57 R58 R59 R61 R62 K64 H65 R71 R72 F89 K92 D96 W98 H120 K123 R124 R125 G126 H173 K174 R175 N176 K177 G178 R187 S223 Q224 R225 V227 K251 E263 H420 Y439 A469 T478 K489 R809 V811 T812 G813 H816 L820 R822 K838 S859 D860 K888 K890 K891 V898 R900 K918 T919 M949 Q1049 Y1057 K1058 V1059 R1060 V1065 |
Binding residue
(residue number reindexed from 1) | S45 L46 R50 R51 R57 R58 R59 R61 R62 K64 H65 R71 R72 F89 K92 D96 W98 H120 K123 R124 R125 G126 H166 K167 R168 N169 K170 G171 R180 S216 Q217 R218 V220 K244 E256 H413 Y432 A462 T471 K482 R653 V655 T656 G657 H660 L664 R666 K682 S703 D704 K732 K734 K735 V742 R744 K762 T763 M793 Q893 Y901 K902 V903 R904 V909 |
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