Structure of PDB 8uv3 Chain A Binding Site BS01

Receptor Information
>8uv3 Chain A (length=514) Species: 223997 (Murine norovirus 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QDLVPAAVEQAVPIQPVAGAALAAPAAGQINQIDPWIFQNFVQCPLGEFS
ISPRNTPGEILFDLALGPGLNPYLAHLSAMYTGWVGNMEVQLVLAGNAFT
AGKVVVALVPPYFPKGSLTTAQITCFPHVMCDVRTLEPIQLPLLDVRRVL
WHATQDQEESMRLVCMLYTPLRTNSPGDESFVVSGRLLSKPAADFNFVYL
TPPIERTIYRMVDLPVIQPRLCTHARWPAPVYGLLVDPSLPSNPQWQNGR
VHVDGTLLGTTPISGSWVSCFAAEAAYEFQSGTGEVATFTLIEQDGSAYV
PGDRAAPLGYPDFSGQLEIEIQTETTKTGDKLKVTTFEMILGPTTNADQA
PYQGRVFASVTAAASLDLVDGRVRAVPRSIYGFQDTIPEYNDGLLVPLAP
PIGPFLPGEVLLRFRTYMRQIDTADAAAEAIDCALPQEFVSWFASNAFTV
QSEALLLRYRNTLTGQLLFECKLYNEGYIALSYSGSGPLTFPTDGIFEVV
SWVPRLYQLASVGS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8uv3 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8uv3 The reversible activation of norovirus by metal ions.
Resolution2.72 Å
Binding residue
(original residue number in PDB)		Q438 D440
Binding residue
(residue number reindexed from 1)		Q420 D422
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0019049 virus-mediated perturbation of host defense response
Cellular Component
GO:0044423 virion component

View graph for
Biological Process
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Cellular Component
External links
PDB RCSB:8uv3, PDBe:8uv3, PDBj:8uv3
PDBsum8uv3
PubMed38236007
UniProtQ2V8W4

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